Clinical Characteristics Of Cerebral Infarction Alleviating Within A Short Time

Through clinical observations, it is found that the proportion of patientswith cerebral infarction who are characterized with a well relief within a shorttime is gradually increasing. Nowadays characteristics of these patientsremains to be elucidated, such as gender, age, risk factors, vascular stenosis,imaging changes and therapy. Exploring these clinical characteristics and thenimplementing clinical interventions which can alleviate neurological deficitsand control risk factors, these patients can be prevented from developing intoprogressive cerebral infarction.Objective:To perform clinical characteristics of cerebral infarction alleviatingwithin a short time, discussing related risk factors.Materials and Methods:The clinical data of patients with acute cerebral infarction wereretrospectively analyzed. All of them were hospitalized patients in No.1Hospital of Jilin University Affiliated Hospital department of neurology andits department II from July2013to September2014, whose onset time wasless than24hours with clear signs of neurologic deficits before treatmentlasting more than1hours; National Institute of Health stroke scale (NIHSS)scores were recorded at the same time every day. Patients whose NIHSS score fell more than or equal to7points within5days were divided intoremission group including64cases, and those whose NIHSS score droppedless than7points would be treated as no-remission group, a total of72cases.The two groups were compared with gender, age, NIHSS score, riskfactors, such as, smoking, alcoholism, hypertension, diabetes and coronaryheart disease(CHD), blood glucose, blood lipid, fibrinogen, vascular stenosis,types of cerebral infarction, cerebral edema and medications.Results:1. For remission group, NIHSS scores on5day after admission weresignificantly less than that on admission(P<0.01), and there was no differencein no-remission group; NIHSS scores of remission group on admission waslower than that of no-remission group. Compared to two groups, thedifference was statistically significant (P<0.01).2. Male ratio in remission group was88%, which was higher than that ofno-remission group, that is56%, with a statistically significant difference(P<0.01).3. Remission group had18cases of diabetes,21cases of hyperglycemia,23cases of smoking; no-remission group combined with43cases of diabetes,49cases of hyperglycemia,39cases of smoking. Compared the two groups,for diabetes and hyperglycemia, there were statistically significant differences;for smoking, significant difference was shown（P＜0.05）. 4. Total vascular stenosis rate was27%in remission group, which was54%in no-remission group, displaying significant difference（P＜0.01）;vascular stenosis rate gave priority to single ones in remission group andvascular stenosis rate was composed mainly by multi-vessel inno-remission group, showing significant difference(P＜0.01); stenosis ofinternal carotid artery(ICA)dominated in remission group, vertebrobasilarartery stenosis in no-remission group, displaying significant difference（P＜0.05）.5. Remission group had9cases with cerebral edema showed by MRI,56cases with anterior circulation infarct(ACI),8cases with posterior circulationinfarction(PCI);In no-remission group, there were29cases with cerebraledema,46cases with ACI,26cases with PCI. Both cerebral edema andinfarction type had significant differences.6.23cases applied urinary kallikrein in remission group,10cases inno-remission group. Compared to two groups, the difference was statisticallysignificant (P<0.01).7. Comparing both two group’ NIHSS scores on14day which were lessthan that on admission (P<0.01), identical to efficient and total effective rates.Conclusions:Clinical characteristics of cerebral infarction alleviating within a shorttime：1. Symptoms of these patients are less severe on admission. 2. The male proportion is higher than that of female generally.3. Patients with diabetes, smoking and hyperglycemia are in smallnumbers.4. Related vascular stenosis rate is low, giving priority to single vascularlesions.5. Patients focus on ACI, showing obvious pathological changes in cortexand light edema degree on MRI DWI.6. Urinary kallikrein has a good clinical efficacy for these patients.7. The infarction has good prognosis.