| Objective: Using fire needle combined with TUM therapy to treat the area and severity of skin lesions,the degree of pruritus,the quality of life score,the Uyghur medical syndrome score and the influence of laboratory index change level and adverse reactions in patients with salty mucous chronic eczema.To observe and explore the clinical efficacy of fire needle combined with Traditional Uyghur medicine(TUM)conventional treatment program of salty Belgham type chronic eczema,so as to provide clinical basis for this therapy.Methods: from December 2018 to December 2019,80 patients with salty Belgham type chronic eczema meeting the inclusion criteria and exclusion criteria in Traditional Uyghur Medical Hospital of Xinjiang Uyghur Autonomous region were randomly selected and divided into treatment group(n = 40)and control group(n = 40).The treatment group was treated with fire needle plus conventional treatment program of TUM(Oral and external medicine treatment,physical therapy),and the control group was treated with TUM only(Oral and external medicine treatment,physical therapy).The lesion area,lesion severity index,pruritus score,dermatosis quality of life score and TUM syndromes score were carried out in the two groups,and the serum eosinophil percentage(EOS)and basophil percentage(BASO)were detected.After 20 ±3 days of treatment,the physical and chemical indexes and scores of the two groups were compared before and after treatment to determine the curative effect.Results: among the 80 patients included according to the shedding criteria,there was 1 case in each of the two groups,and the final qualified case was 78 cases.There is no statistical significant difference in the general data of the patients,such as age,gender,career,marital status and course of disease between the two groups(P > 0.05),but there is still comparability between the two groups.(1)at the end of the treatment,the total effective rates of the two groups were as follows: there was 9 cured cases,21 markedly effective cases,8 effective cases,and 1 ineffective case in the treatment group,and the total effective rate was 97.44%;in the control group,4 cases were cured,18 cases were markedly effective,13 cases were effective,4 cases were ineffective,and the total effective rate was 89.74%.The difference was statistically significant by rank sum test(P < 0.05),indicating that the treatment group had better efficacy than the control group.(2)The two groups were compared in the scores of TUM syndromes,compared with the treatment group and the control group before treatment(P <0.05),with statistical significance.after treatment,the two groups were compared(P> 0.05),the difference was not statistically significant.(3)at the end of the treatment,the EASI scores of the two groups were compared after treatment(P < 0.05).There is statistically significance between the two groups.(4)at the end of the treatment,the pruritus scores of the two groups were compared after treatment,there is significant difference between the two groups(P < 0.01),and there is significant difference between the two groups(P < 0.05).(5)at the end the treatment,the DLQI scores of the two groups were compared before and after treatment,and there is significant difference between the two groups after treatment.(6)at the end of the treatment,the total scores of the two groups after treatment were compared,and there is significant difference between the two groups before and after treatment(P < 0.05),and between the two groups after treatment(P < 0.05).(7)at the end of the treatment,the percentage of serum eosinophil and basophil were detected and compared between the two groups.There is no significant difference in serum EO% between groups and within the control group,but there is significant difference in the treatment group before and after treatment.There is no significant difference in serum BAEO% between groups and within groups.(8)there were no adverse event in the two groups during the treatment showing relative safety of the program.Conclusion: Treating salty mucous type chronic eczema with fire needle combined with TUM therapy can effectively improve skin lesions and systemic symptoms.Its curative effect is better than that of TUM treatment group.There are no obvious adverse reactions and it is laid out for clinical application. |
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