Analysis Of Risk Factors For ICU Acquired Weakness And Its Prognosis

Objective:To explore the risk factors and prognosis of acquired weakness in intensive care unit(ICU).Methods:Retrospective analysis of 245 patients in the intensive care unit of the First Affiliated Hospital of Kunming Medical University(No.3 floor of ICU,Center ICU,and Emergency ICU)from May 2018 to October 2018,using the Medical Research Council,s muscle strength score The table is used to diagnose ICU AW and is divided into ICUAW group and non-ICUAW group according to whether it is diagnosed as ICUAW.The basic conditions of the patients were recorded:age,gender,body mass index and acute physiology and chronic health status scoring system ? scores;biochemical indicators at the time of admission included:serum albumin,lactic acid,blood sugar,nutrient supply time and manner(Intestinal,parenteral+enteral,total parenteral);whether to take blood purification treatment,neuromuscular blockers,norepinephrine,brake;whether there is sepsis,multiple organ dysfunction;mechanical ventilation time and ICU Hospitalization time;the patient's recent(from the beginning of ICU to 28 days after discharge)and the long-term(6 months after discharge)deaths were recorded and the patient's long-term ability to live was assessed.Using spssl7.0 statistical software,?2 tests,t test,rank sum test,and two-class logistic multi-factor regression analysis were used to calculate the correlation between various factors and ICUAW.P<0.05 was considered statistically significant.Results:1?The incidence of ICUAW in intensive care unit of the First Affiliated Hospital of Kunming Medical University was 47.8%;the recent mortality rate in ICUAW group was higher than that in non-ICUAW group(P<0.05).There was no significant difference in long-term mortality between the two groups.Academic significance(P>0.05);2?Univariate analysis showed that the ICUAW group was compared with the non-ICUAW group.The parameters included age,gender,APACHE ? score,mechanical ventilation time,and ICU hospitalization time.The biochemical indicators at the time of admission included serum albumin,lactic acid,blood glucose,nutrient supply time,and nutrition.Supply,blood purification treatment,neuromuscular blockade,norepinephrine,brake,sepsis,multiple organ dysfunction were statistically significant,P<0.05.The body mass index at admission was not statistically significant between the two groups(P>0.05).3?Two-category logistic multivariate regression analysis indicated that lactate level,APACHE II score,mechanical ventilation time,ICU hospitalization time,and MODS were statistically significant at admission;4?The long-term non-ICUAW patients had higher daily living ability after-discharge than ICUAW patients,P<0.05,which was statistically significant.Conclusion:1?Age,gender,serum albumin,lactic acid,blood glucose,time and mode of nutrient supply,blood purification,neuromuscular blockers,norepinephrine,brakes,sepsis and the occurrence of ICUAW.2?APACHE ? score,mechanical ventilation time,ICU stay,lactic acid at admission,and MODS were independent risk factors for ICUAW.3?Patients with ICUAW had a higher near-term mortality than non-ICUAW;patients with ICUAW had a lower long-term ability to live after discharge from patients who were not ICUAW.