Clinical Observation On The Treatment Of Obese Polycystic Ovary Syndrome With The Combination Of Guiluo's Tiao Zhou Prescription And Acupoint Catgut Embedding

Objective:Through the clinical study on the treatment of obesity polycystic ovary syndrome with the combination of Guiluo's Tiao Zhou prescription and acupoint catgut embedding,the clinical efficacy and safety were observed,so as to provide reference ideas and methods for the clinical treatment of obesity polycystic ovary syndrome.Methods:This topic selection in October 2018 to 2019 in November to rui kang affiliated hospital of guangxi medical university during gynecologic clinic on 60 patients with into standard,using the random number table method were randomly divided into treatment group(Guiluo's Tiao Zhou prescription and acupoint catgut embedding)and the control group(western medicine group combined life instruction),each group of 30 patients,continuous 3 months after treatment,compared before and after the treatment of menstrual cycle and TCM syndrome score,BMI(Body Mass Index,BMI),waist-to-hip ratio(the Waist-to-hipratio,WHR)basis,clinical pregnancy rate,serum sex hormone(FSH,LH,T,LH/FSH)level,Fasting glucose,Fasting plasma glucose,FPG),Fasting insulin(FINS)and insulin resistanceindex(HOMA IR),and other changes,and followed up for 3 months after treatment to evaluate the TCM symptoms curative effect.Statistical software SPSS20.00 was used for data analysis to scientifically evaluate the clinical efficacy and safety of guiluo tiuzhou prescription combined with acupoint cat-embedding in the treatment of obese polycystic patients.Results:(1)TCM symptoms: the effective rate of the treatment group was92.85%;The effective rate of the control group was 79.31%(P<0.05).(2)Efficacy of menstrual cycle: before and after treatment,in and between the two groups,there were statistically significant differences(P<0.05).(3)TCM syndrome score: after treatment,there were statistically significant differences in the TCM syndrome score between the two groups before and after treatment(P<0.01),and between the two groups after treatment(P<0.01).(4)Comparison of observed BMI indicators and efficacy of weight loss: after treatment,the BMI indicators of the two groups before and after treatment were compared within the group,showing significant differences(P<0.01).The BMI of the two groups after treatment was compared: there was a significant difference(P<0.01).After the treatment,the efficacy of weight loss in the two groups was evaluated,and the effective rate of weight loss in the treatment group was 89.29%.The effective rate of weight loss in the control group was 68.97%,with no statistically significant difference(P>0.05).(5)Comparison of WHR: after treatment,there were significant differences between the two groups before treatment and within the WHRgroup after treatment(P<0.01).After treatment,the difference between the two groups was statistically significant(P<0.05).(6)Comparison of fasting blood glucose(FPG),fasting insulin(FINS)level,and insulin resistance index(IR): before and after treatment,FPG and IR in the two groups showed significant differences(P<0.01).Comparison in the FINS treatment group showed statistically significant difference(P<0.05),comparison in the control group showed significant difference(P<0.01),and comparison between the two groups after treatment showed no statistically significant difference(P>0.05).(7)Comparison of serum sex hormones(FSH,LH,LH/FSH,T):after treatment,there was no statistical difference between the two groups(P>0.05).After treatment,there were significant differences between the two groups in the LH group(P< 0.01),and no statistically significant differences between the two groups after treatment(P> 0.05).Comparison of serum basal LH/FSH in the group after treatment: the difference was significant(P<0.01);comparison between the groups: the difference was statistically significant(P<0.05).Comparison of serum base T in and between groups after treatment showed significant difference(P<0.01).(8)Clinical pregnancy rate:comparison of pregnancy rate between the two groups after treatment: the difference was statistically significant(P<0.05).The clinical pregnancy rate was 38.89% in the treatment group and 10.53% in the control group.(9)Safety comparison: no serious adverse reactions were found in the two groups of patients during the treatment,and no obvious abnormalities were found inthe two groups of patients before and after treatment by comparing the relevant safety examination indicators(three major routine procedures,liver and kidney functions and electrocardiogram).Conclusion: The Guiluo's Tiao Zhou prescription and acupoint catgut embedding can be effectively improve obese polycystic ovary syndrome(PCOS)patients with menstrual cycles,fasting plasma glucose(FPG),fasting insulin(FINS)levels,reduce insulin resistance index(IR),reduced serum levels of sex hormones LH,T,LH/FSH,body mass index,waist-to-hip ratio and TCM symptom score,and clinical curative effect,no obvious adverse reactions.