Data Mining Study Of Hu Guojun's Famous Old Chinese Medicine In Treating Pulmonary Nodules

Objective:Using data mining technology,the analysis and summary of Professor Hu Guojun's knowledge of pulmonary nodular disease and the rules of medication prescriptions for treating pulmonary nodules were summarized.Method:Collect the medical records of patients with pulmonary nodules who attended the outpatient clinic of Professor Hu Guojun from January 2017 to December 2019 by way of outpatient follow-up,etc.select outpatient medical records that meet the criteria for inclusion in the subject,initially organize and form a complete medical record,and then organize the medical record Relevant information was entered into the "Traditional Chinese Medicine Data Processing Software V3.1" of the Information Center of the Traditional Chinese Medicine Hospital of Anhui Province.It was analyzed through data mining methods,and the mining results were analyzed and summarized.The results were submitted to Professor Hu Guojun for review and modification.Come to relevant conclusions.Results:Through a variety of data mining techniques,the medical records of 103 patients with pulmonary nodules collected from a total of 377 consultations were analyzed,and the following results were concluded:1.Four common types of lung nodules:(1)deficiency of lung and spleen,dampness of phlegm dampness.(2)deficiency of phlegm heat,deficiency of lung,qi and yin.Evidence.(4)phlegm and blood stasis are interlinked,and the lungs are not smooth.2.According to the frequency of total drug appearance,the top 30 are: scallion,saponin,coix seed,ginseng,raw oyster,Fritillaria,Astragalus,Astragalus,Schisandra,Kunbu,seaweed,gardenia,Pseudostellaria heterophylla,Shanci mushroom,Scrophularia spp,Golden boiling grass,Melon bark,Prunella vulgaris,Bupleurum spp,Dead silkworm,Loquat leaves,Lily,Fructus citrifolia,Zhimu,Cicada molting,Platycodon grandiflorum,Ophiopogon,Peach kernel,Poria,Ginger pinellia.3.Fifteen commonly used medicine pairs:(1)Fritillaria citrifolia,Amaranth shellfish.(2)Saponin hornthorn,Amaranth shellfish.(3)Coix kernel,Amaranth shellfish.(4)Nansha ginseng,Amaranth shellfish.(5)Raw oysters,Amaranth Forma.(6)Coix kernels and saponins.(7)Raw oysters and saponins.(8)Cotoneaster and saponin.(9)Saponins and coix.(10)Nansha ginseng and coix kernels.(11)Raw oysters and barley kernels.(12)Cockleshells and barberry kernels.(13)Fritillaria cirrhosa and Nansha ginseng.(14)Saponaria serrata and Nansha ginseng.(15)Coix ranch and Nansha ginseng.4.Thirteen commonly used drug combinations:(1)Coix kernel,saponin,snail shell.(2)Raw oysters,saponaria,scallion shell.(3)Saponin,horns,scallion shell.(4)Nansha ginseng,Coix seed,Cockleshell.(5)Raw oyster,Coix seed,Cockleshell.(6)Nansha ginseng,Coix seed,Saponaria spinosa.(7)Raw oyster,Coix kernel,Saponaria spinosa.(8)Cockleshell,Coix seed,Saponaria sibirica.(9)Nansha ginseng,Coix chinensis,Saponaria sibirica,scallion.(10)Raw oysters,Coix chinensis,Saponaria spp.,Scallion.(12)Saponaria,seaweed,kelp.(13)Coix kernel,seaweed,kelp.5.Seven new prescriptions:(1)Astragalus,Radix Pseudostellariae,Schisandra,efficacy:nourishing the lungs,strengthening the spleen,nourishing qi and nourishing yin.(2)Scrophulariae,Prunella vulgaris,Shanci mushroom.efficacy: clearing heat and detoxifying,dissolving phlegm and dissolving.(3)Scutellaria baicalensis,Nanshen ginseng,Coix kernel,Scallion shell,Saponin thorns,efficacy: clearing heat and nourishing yin,softening and dispersing knots.(4)Bupleurum,coriander shell,platycodon grandiflora,Poria cocos,ginger pinellia,efficacy: regulating qi,depressing,reducing Phlegm scattered.(5)Seaweed,kelp,raw oysters,black ginseng,prunella,Zhejiang fritillary,efficacy: clearing heat and reducing phlegm,soft and firm.(6)Stiffsilkworm,cicada,golden boiling grass,loquat leaf,loquat Gardenia,efficacy: Xuansu Taiyin,phlegm and cough.(7)Lily,Ophiopogon,peach kernel,Zhimu,efficacy:nourishing yin,clearing heat,dispersing stasis.6.One core prescription,its drug composition is: scallion,saponin,astragalus,Radix Pseudostellariae,Scutellaria baicalensis,Schisandra chinensis,black ginseng,raw oysters,mandarin mushroom,seaweed,kombu,barley,ginseng,Zhejiang Fritillaria Bitch.Conclusion:The data mining method is used to process the prescriptions of traditional Chinese medicine in the outpatient records of patients with pulmonary nodules.and the results obtained are analyzed to summarize the basic rules of distinguishing and treating pulmonary nodules by Professor Hu Guojun,mainly as follows:1.In terms of etiology and pathogenesis,Professor Hu Guojun believes that pulmonary nodules belong to the category of "pulmonary volume" in traditional Chinese medicine.The pathogenesis is based on the deficiency of the lungs,exogenous sexism,inappropriate eating,loss of work and rest,insufficient endowment,internal emotional damage,etc.The effect is to cause the lungs to lose blood,and the fluid to be dispensed is unfavorable.Condensation is sputum,and the phlegm is hot for a long time.Qi,stasis,and heat are not cemented,obstructing the lungs,the lungs are not smooth,and become a product over time.The pathological properties are based on deficiency and normality,the positive deficiency(qi deficiency,yin deficiency,and yang deficiency)as the basis,and the evil reality(phlegm dampness,blood stasis,qi stagnation,fiery fever)as the standard.2.In the treatment,clinical syndromes always clear the phlegm and heat,soften and disperse stagnation,promote blood circulation,improve qi and nourish yin,strengthen the spleen,improve lungs,and relieve qi and depression.The patient's clinical symptoms,constitutional bias,disease course,comorbidities,etc,while referring to theclassification of Western medicine pathology,comprehensive differentiation of syndromes,"according to the conditions of the individual".The medication should not be too cold,nor should it be blindly attacked.It takes time to protect the righteousness,and the period is flat.Based on Professor Hu Guojun's knowledge of the etiology,pathogenesis and treatment of pulmonary sarcoidosis,and the prescription rules obtained from data mining,the four most common clinical types and treatment principles of pulmonary nodules are summarized.see the discussion section for details.3.The core prescriptions obtained through data mining analysis have the functions of clearing phlegm and heat,softening and dispersing nourishment,and nourishing qi and nourishing yin.Through reasonable addition and subtraction,it can be applied clinically to the treatment of various syndromes of pulmonary nodules.