Clinical Analysis Of Oral And Maxillofacial Space Infection With Diabetes In Zunyi Area

Objective: 1.By studying and analyzing the characteristic clinical manifestations of patients with oral and maxillofacial space infection complicated with diabetes mellitus in Zunyi area and the factors influencing the therapeutic effect,this paper provides certain data support for the prevention of diseases,the prevention of serious complications and the reduction of hospitalization time in clinic.2.By studying and analyzing the distribution of pathogenic bacteria and the results of drug susceptibility test,it will be helpful to prevent the invasive operation of oral and maxillofacial region in patients with diabetes mellitus and to provide empirical medication for patients with diabetes when they are admitted to hospital with interstitial infection.Methods: Medical records of inpatients with oral and maxillofacial space infections discharged from the oral and maxillofacial surgery ward of the Affiliated Stomatological Hospital of Zunyi Medical University from January 2016 to January 2018 were collected,including basic information of patients,pre-admission and post-admission information.Excluding those who have incomplete medical records and have not received standard treatment,they are grouped according to whether they have diabetes mellitus or not,and the data are analyzed statistically.The characteristic clinical manifestations of diabetes mellitus and non-diabetes mellitus were compared and analyzed between groups.Patients with diabetes mellitus and non-diabetes mellitus were excluded from the medical records without incision and drainage.The risk factors were analyzed by logistic regression through univariate analysis and factors related to the treatment outcome(hospitalization days and complications)of patients with oral and maxillofacial space infection.Descriptive statistical analysis of pathogenic bacteria distribution and drug susceptibility test results.Results: In the clinical characteristic analysis,497 cases were included,including 56 cases of diabetes mellitus and 441 Cases of non-diabetes mellitus.1.The study found that the characteristic clinical manifestations of diabetic patients compared with non-diabetic patients were as follows:(1)the age of patients was older;(2)multi-gap infection was more common,the number of infection gap was more frequent,and infection involved neck more frequently;(3)the prevalence of other systemic diseases was higher;(4)the whole body condition was more critical at admission,the number of white blood cells,the percentage of neutrophils and blood sugar and water at admission.level higher;(5)long antibiotic use time and long hospitalization days after admissionr.2.Distribution of infection space in diabetic group: submandibular space is most frequently involved,followed by buccal space and masseter space;in non-diabetic group,the most frequently involved is buccal space,followed by submandibular space and masseter space.396 cases were included in the analysis of the effect of treatment.It was found that patients came from rural areas and multi-gap infection was a risk factor for hospitalization days.It was found that patients from rural areas and multiple interstitial infections were risk factors for complications.Gram-positive bacteria were common in the diabetic group in bacteriological culture,among which Streptococcus was the most common,followed by Streptococcus constellation,Streptococcus pharyngis,Streptococcus Gordon and Streptococcus Miller;Klebsiella pneumoniae was the most common gram-positive bacteria in the gram-negative bacteria;Gram-positive bacteria were common in the non-diabetic group,among which Streptococcus constellation,Streptococcus pharyngitis,Streptococcus mitis the most common.Klebsiella pneumoniae,Pseudomonas aeruginosa,Eikenia erosion and Proteus mirabilis were cultured in Gram-negative bacteria.Conclusion: 1.Compared with non-combined diabetic patients,oral and maxillofacial infections in Zunyi area showed characteristic clinical manifestations of older patients,more critical illness at admission,poor prognosis and more complicated treatment options.The analysis found that patients from rural areas,diabetes and multiple interstitial infections were risk factors for treatment outcomes.2.Diabetic patients with maxillofacial space infection are mostly infected by Streptococcus and Klebsiella pneumoniae.Clinical empiric and preventive drugs can be used with cefuroxime or cefotaxime combined with ornidazole,and finally according to drug sensitivity test.