The Clinical And Bacteriological Analysis Of The Diabetic Maxillofacial Space Infections

Objective To analyze the clinical characteristics of maxillofacial space infection between the diabetic and non-diabetic patients.By exploring the common pathogenic bacteria and antibiotic sensitivity analysis of diabetic patients,to guide the clinical medication.Methods The research object of oral and maxillofacial surgery,Oingdao Municipal Hospital affiliated to Qingdao University from December 2014 to December 2016,61 cases were treated in the oral and maxillofacial space infection concurrent abscess incision and drainage in hospitalized patients,and according to the presence or absence of diabetes were divided into diabetic group and non-diabetic group.The age,sex,source of infection,pathogen,antimicrobial susceptibility,fasting blood glucose,total white blood cell count,neutrophil percentage,and hospital stay were compared between the two groups.SPSS.19.0 software package was used to carry out the t test of the measurement data,and the count data were analyzed by chi square test with p< 0.05,which was statistically significant.Results1.There were 26 males and females in the diabetic group,included males 17 and females 9.There were 35 males and females in the non-diabetic group,included males 21 and females 14.The diabetic group accounted for 42.6% of the data,and there was no significant difference between the two groups(chi square test,P=0.184).2.The mean age of diabetic group(57.25±18.76)was significantly higher than that of non-diabetic group(33.41±26.45).3.The mean fasting blood glucose level in diabetic group(10.32±2.81)was significantlyhigher than that in non-diabetic group(4.94±0.54).The morning fasting blood WBC count had no significant difference bettwen diabetic group[(15.78±5.59)×109/L]and the non diabetes group[(15.43±5.59)×109 /L].The morning fasting blood average percentage of neutrophils in diabetic group[(83.99±9.86)%] was significantly higher than non-diabetic group[(72.87±16.26)%].4.Odontogenic infection are the most common source of infection in two patients,the most frequently involved spaces were found in the submandibular space,followed by the clearance and clearance of masseter muscle chin,most pathogens were Streptococcus,accounted for 57.69%,60%,followed by Staphylococcus,in addition,the detection of diabetes Klebsiella pneumoniae was significantly higher than that in non-diabetic group.5.The two groups of common pathogenic bacteria were sensitive to vancomycin 100%,but also to levofloxacin and cefotaxime.6.The number of days in the diabetic group(11.12±5.62)was significantly higher than that in the non-diabetic group(7.77±2.83).Coclusion For the diabetic patients with maxillofacial space infection,we could use levofloxacin and cefotaxime for the conservative treatments when the results of the bacterial culture and drug susceptibility test are not obtained.To the oral and maxillofacial anatomy,we could also use anti-anaerobic agents such as Tinidazole together.But the final situation of medication is based on the result of the drug susceptibility test.