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Correlation Between The Drug Sensitive Test Technology Of Gelatinous Tumor And Prognosis Of Colorectal Cancer

Posted on:2020-06-18Degree:MasterType:Thesis
Country:ChinaCandidate:W L LuFull Text:PDF
GTID:2404330596496283Subject:Surgery
Abstract/Summary:PDF Full Text Request
Objective:Objective To study the correlation between the drug sensitive test technology of gelatinous tumor and prognosis of colorectal cancer..Methods:311 cases of patients with colorectal cancer in our hospital from June 2012 to June 2017 were selected and divided into two groups according to the chemotherapy plan recommended by the CD-DST,including 132 cases undergoing the drug sensitivity test and finishing the chemotherapy according to the results(89 high-sensitive cases and 43low-sensitive cases),the control group with 179 cases without drug sensitive test and finishing the chemotherapy according to the NCCN guidance,and the age,gender,and clinical staging of patients were counted,and the survival state of patients was followed up,and the total survival period of each group was counted.Results:The differences in the age(?~2=0.651,P=0.42),gender(?~2=1.225,P=0.268)and T staging(?~2=2.684,P=0.261)were not Statistically Significant(P>0.05),and in the patients in clinical ?,the survival period in the experimental group was longer than that in the control group,the different was statistically significant(P=0.029),and the 3-year survival rate in the experimental group and in the control group was respectively 88.4%and 60.2%,and the survival period in the high-sensitive group was longer than that in the low-sensitive group,the different was statistically significant(P=0.035),and the 3-year survival rate in the high-sensitive group and the low-sensitive group was respectively 94.2%and 81.2%.Conclusion:The drug sensitive experimental technology in guiding the chemistry treatment of patients after the stage ? colorectal cancer can prolong the survival period of patients,which is of a certain guidance significance to the individualized treatment of rectal cancer.
Keywords/Search Tags:CD-DST, Colorectal cancer, Chemotherapy, Individualized treatment
PDF Full Text Request
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