| Background Percutaneous renal colostomy surgery is a common clinical means,providing adequate drainage system,can be used to reduce urinary tract obstruction,etc.JYS is a kind of long-acting bacteriostatic materials,which was used for preventing of percutaneous renal fistula of postoperative infection.Several studies have suggested that long-acting bacteriostatic materials can effectively reduce the incidence of urinary tract infection compared to other methods,but there was no study suggest that long-acting bacteriostatic materials could effectively improve the incidence of secondary urinary tract infection compared to other measures for postoperative infection of nephrostomy.This study compared the effects of long-acting antimicrobial materials(Jude Yu Shen)with usual care on the prevention of secondary urinary tract infections of nephrostomy through randomized controlled studies.Objective To review the effects of Long-term antibacterial materials(JUC)in the prevention of postoperative infection for nephrostomy.Methods Randomized controlled trial design was used to select 82 cases of benign prostatic hyperplasia treated with percutaneous nephrostomy in our hospital from January 2017 to December 2017.They were randomly divided into two groups before operation.The experimental group was treated with JUC antibacterial material treatment,the control group applied the postoperative care,without JUC treatment.The observation outcomes include: the incidence of clinical symptoms,the analysis of blood routine tests,the urinary tract infection rate,the infection rate at the exit site,the incidence of bacteriuria after the catheterization,the cost-effectiveness ratio and side effects between the two groups.Result This randomized controlled trial enrolled 82 patients,each group has 41 participants.The results suggested as following: a.There was no statistically significant difference(P>0.05)in the fever rate on the first day,and pain incidence rate on the fifth day between the two groups.The difference in other aspects between two groups was not statistically significant.b.The difference in neutrophil numbers before and after extubation between the two groups was not statistically significant;There was no significant difference in the number of leukocytes between the two groups before and after extubation(P >0.05).c.The rate of urinary tract infection in the experimental group from the 1-7 days after implantation of the catheter showed a downward trend(14.6%-4.8%).The positive rate of the bacteria in the control group showed an insignificant upward trend(24.3%-34.1%).There was significant difference in the number of cases of urinary tract infection among the groups in day 5 and 7(P<0.05).d.The incidence of secretions at the outlet of the experimental group from the 1-7 day decreased(34.1%-4.8%)in the control group.The secretion at the outlet site showed a significant downward trend(80.5%-9.8%).There was significant difference in the incidence of secretions at the outlet of the catheter between the two groups(P <0.05)at the 1st day.e.The cost benefits analysis of intervention group was 32.30 RMB,and 5.19 RMB for control group,the cost benefits for both group was 185 RMB;f.There was no adverse reaction of systemic and urethral meatus in the experimental group,and the adverse reaction rate was 9.7% in the control group.There was no significant difference in the side effects incidence rate between two groups(P >0.05).Conclusion Current randomized controlled study suggested that long-acting antibacterial materials is an effective,safe,and economical preventive measure for secondary urinary tract infections after nephrostomy.In conclusion,this study suggested that long-acting antimicrobial materials could effectively prevent of infections of percutaneous nephrostomy. |
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