Clinical Observation Onhot Syndromes-related Cerebral Infarction-associated Pneumoniatreating With Sputum-fire Prescription

Objective:In this study,we investigated the clinical efficacy of sputum-fire prescription in the treatment of hot syndrome cerebral infarction associated pneumonia,and observed the clinical efficacy of Huhuo Huoxue in patients with hot syndrome type cerebral infarction associated pneumonia,the improvement of symptoms of traditional Chinese medicine,NIHSS score and safety evaluation.With the influence of other aspects,the clinical curative effect of treatment of hot syndrome type cerebral infarction-associated pneumonia was investigated in order to provide clinical evidence for the treatment of hot syndrome cerebral infarction associated pneumonia.Methods:Hospitalized patients from the Huangdao District Hospital of Qingdao City and the Department of Encephalology of the Haici Medical Group were selected comparing the inclusion criteriaand the principle of random number table,anddivided into two groups,the control group(33 patients)and the treatment group(31 patients).The control group were under conventional treatment according to the Chinese Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke(2014),andthe treatment group were given either oral or nasal feeding on the basis of conventional treatment.Both groups took 14 days for treatment.After the end of the clinical trial,the total clinical efficacy,TCM syndrome scores,relevant indicators of pneumonia(T,WBC,CRP,PCT),NIHSS score,and liver and kidney function were observed in the two groups.Perform statistical analysis and analyze the results.Results:1.In terms of total clinical efficiency,the improvement rate in the treatment group was 93.55%,and the improvement rate in the control group was 84.85%.Between the two groups,the total effective group was P=0.003<0.01.The difference was statistically significant,indicating that the treatment group The rate of improvement was significantly better than that of the control group.2.In the aspect of TCM symptom improvement: In the TCM syndrome group beforeand after treatment,the two groups P=0.000<0.01.The differences between the two groups are statistically significant,indicating that both groups can significantly improve TCM syndromes;After the comparison between TCM syndrome groups,P=0.02<0.05,there was a difference between the two groups,and the treatment group score(9.03±6.37)was lower than the control group(13.18±7.48),indicating that the treatment group was superior in improving TCM syndromes in the control group.3.NIHSS scores: Compared with the NIHSS scores before and after treatment in the two groups,P=0.000<0.01,indicating that both groups can improve the symptoms of neurological deficits,but the difference between the NIHSS scores after treatment in the two groups,P=0.56>0.05.There was no difference in NIHSS scores between the two groups after treatment,but the treatment group(6.29±3.41)was lower than the control group(8.06±3.67),indicating that the treatment group was superior to the control group in improving the symptoms of neurological deficits.4.Pneumonia related indicators: In terms of pneumonia-related indicators(T,WBC,CRP,PCT),the comparison between the control group before and after treatment with PCT,T,WBC,and CRP,P = 0.000 <0.01,indicating that the control group had significant before and after treatment Difference;Treatment group,T,WBC,CRP,PCT group before and after treatment,P = 0.000 <0.01,indicating that the treatment group had significant differences before and after treatment;the above shows the two indicators of pneumonia after treatment(T,WBC,CRP,PCT).Both improved,but there was no difference between the WBC,CRP,T,and PCT groups after treatment in the two groups,indicating that the efficacy of the two groups was comparable after treatment.5.In terms of drug safety: ALT,AST,BUN,Cr were not statistically changed before and after treatment in both groups(P>0.05),and the difference was not statistically significant,indicating that both groups had liver and kidney function.Conclusion:The combination of sputum-fire prescription conventional western medicine can increase the total clinical efficiency of heat syndrome cerebral infarction associated pneumonia,significantly improve the patients' TCM syndromes,and can significantly improve the neurological deficit symptoms and pneumonia-related indicators of patients.