The Research Of Syndrome Differentiation And Treatment Of Xue Zheng Based On Zhang Cigong's Medical Records

1 Research purposesThis study aims to collect the medical records related to the treatment of blood syndrome by Zhang Cigong,summarize and analyze the differentiation ideas and medication rules of Zhang Cigong's treatment of blood syndrome,which reflected his academic thinking,and explore the origin of blood syndrome from classic works and his teachers to reflect their effect on Zhang Cigong.This research can provide reference for improving the clinical efficacy of traditional Chinese medicine treatment of blood syndrome,and new ideas for the inheritance of famous Chinese doctor's medical experience.2 Research methodsThis study mainly uses data mining and personal comprehension method to analyze the differentiation thought and medication rules of Zhang Cigong's treatment of blood syndrome.The data mining method mainly includes frequency statistics and association rules.Frequency statistics is used to count the symptoms,the common Chinese medicine and their property,taste and meridian and Chinese patent medicine of blood syndrome.Association rules refers to the drug association between two flavors of Chinese medicine or group combination and the association between symptoms and drugs.And the results of the association rules were visualized by Cytoscape 3.6.0 software.The personal comprehension method is mainly used for the analysis of typical medical cases and the analysis of the origin of blood syndrome by Zhang Cigong.The typical medical cases analysis is based on the treatment of blood syndrome cases by Zhang Cigong,and the selection of the medical treatment cases have the number of visits not less than twice and the curative effect is improved or cured,and two cases of misdiagnose and mistreatment.Based on the "Yellow Emperor's Internal Classics""Golden Chamber" "Clinical Guide Medical Case" "Treaties on Blood Disorder" "Ding Ganren Medical Records" to reflect their effects on Zhang Cigong including theory.therapy,prescription and medicine.3 Research results(1)The related symptoms of blood syndrome are menstrual dripping,hematochezia,hemoptysis,blood in the sputum,epistaxis,menstrual collapse.haematemesis,hematuria,gingival hemorrhage,tongue bleeding,purpura;the commonly used traditional Chinese medicines are E Jiao,Xian Hecao,Shu Dihuang,Han Liancao,Wu Weizi,Sang Baipi,Bai Shao,Mai Dong;the frequency of four properties of commonly used traditional Chinese medicines are cold,lat,warm and slightly cold,slightly warm,cool,hot;the frequency of five tastes of commonly used traditional Chinese medicine are sweet,bitter,pungent,acerbity,acid,salty,light,slightly bitter,slightly sweet,slightly Pungent;the frequency of meridians of commonly used traditional Chinese medicine are liver.Kidney,lung,heart,spleen,stomach,large intestine,gallbladder,bladder,small intestine,pericardium;the frequency of commonly used Chinese patent medicines are Zhen Ling Dan,Dai Ge San,Liang Yi Gao,Shi Hui Wan,Qian Jin Zhu Che Wan,Xia Ku Cao Gao,Shi Xiao San,Wei Xi Wan.(2)According to the degree of support of association rules,two flavors of Chinese medicine are Shu Dihuang—E Jiao,Xian Hecao—E Jiao,Wu Weizi—E Jiao,Shu Dihuang—Xian Hecao,Mo Hanlian—E Jiao;the group combinations are Xian Hecao,Shu Dihuang—E Jiao,Shu Dihuang,Wu Weizi—E Jiao,Xian Hecao,Mo Hanlian ?E Jiao;the combinations between symptoms and drugs are menstrual collapse—E Jiao,menstrual collapse—Shu Dihuang,menstrual collapse—Xian Hecao.menstrual collapse—Qu Mai(3)In the typical medical cases,there is one case of gingival hemorrhage which was differentiated as yin deficiency after the febrile disease;two cases of hemoptysis which were differentiated as yin deficiency and stagnant heat;one case of haematemesis which was differentiated as gastric ulcer,one case of hematuria which was differentiated as spleen and kidney deficiency;two cases of hematochezia which were differentiated as spleen deficiency and excessive damp—heat;two cases of menstrual dripping which were differentiated as blood stasis and yang deficiency;one case of misdiagnosed hematuria was showed by the effectiveness after removing Fu Zi and Dang Gui;one case of mistreated hemoptysis was showed by the continuing hemoptysis after the use of warm medicine.(4)For the origin of blood syndrome,Zhang Cigong emphasized the emotions at the basis of "Yellow Emperor's Internal Classics",pathogenesis were included deficiency and heat evil,and Zhang Cighong still was aware of the seriousness of drinking;Zhang Cigong used the prescriptions from "Golden Chamber" such as Huang Tu Tang and Bai Tou Weng Tang;Zhang Cigong also chose the Wei—Qi—Ying—Xue as the differentiated thought from "Clinical Guide Medical Case";Zhang Cigong adopted hemostasis,dispersing blood stasis,pacifying blood,reinforcing deficiency talked by "Treaties on Blood Disorder" and treated flexibility;Under the guidance of Ding Ganren,Zhang Cigong followed the method of the combination of Jing Fang and Shi Fang,and showed his idea of the technological combination of Chinese and Western.4 Research conclusions(1)Zhang Cigong treated blood syndrome based on Xu and Shi syndrome differentiation.The Xu syndrome refers to the deficiency of qi,xue,yin.yang,Shi syndrome refers to the excessive heat evil and blood stasis as well as.(2)Zhang Cigong focuses on E Jiao,Xian Hecao,Shu Dihuang to nourish yin,blood,qi and stop bleeding.The commonly used traditional Chinese medicine have cold and warm properties,which cold is the major properties;the commonly used traditional Chinese medicine have sweet and bitter tastes;the commonly used traditional Chinese medicine attributed to liver,kidney,and then to heart,lung,spleen,stomach.(3)Zhang Cigong also made the two flavors of Chinese medicine,E Jiao,Xian Hecao,Shu Dihuang nearly were the leader medicine,mainly nourishing yin and stopping bleeding,and taking account of the supply of qi.xue,yang,clear of the heat and blood stasis,having six categories,combination of nourishing yin and stop bleeding:E Jiao—O Jie,E Jiao—Xiao Ji,Mo Hanlian—Xian Hecao.Shu Dihuang—Xian Hecao;combination of nourishing xue and qi:Huang Qi—Shu Dihuang,Xian Hecao—Shu Dihuang;combination of nourishing yang and yin:Du Zhons—Shu Dihuang,Xu Duan—Shu Dihuang;combination of nourishing ying:Mo Hanlian—Nv Zhenzi;combination of clearing heat:Sang Baipi—Zhi Mu,combination of circulating blood:Qu Mai—Yi Mucao,Chuan Xiong—Qu Mai.(4)According to the different position of blood syndrome,Zhang Cigong had different ways,for example,treating hemoptysis with Bu Fei E Jiao Tang,treating haematemesis with gastric ulcer experienced prescription;treating hematochezia with Bai Tou Weng Tang,Huang Tu Tang;treating menstrual dripping with Yi Mu Qu Xiong Tang;treating menstrual collapse with Gu Beng Jiu Tuo Fang.(5)Zhang Cigong payed attention to staged treatment,especially nourishing the spleen and stomach after the bleeding.(6)Zhang Cigong still used Fu Zi to treat the blood syndrome.(7)Zhang Cigong advocated the classics and the various thoughts,but not limited to this,such as the creative proposal to treat peptic ulcer with protecting mucosa therapy and appreciated the implementation of the combination of Chinese and Western medicine,and fully demonstrates his "Inheritance and Innovation" Academic knowledge of new knowledge.