Observation And Research On Long-term Efficacy Of TCM Chronic Disease Management Program On EB Virus Positive Population

PurposePreliminary investigation of EB virus infection in Guangzhou population,establishment of personal information and TCM constitution database,analysis of the epidemiological characteristics and TCM constitution characteristics about EB virus infection.Besides,the management plan of traditional Chinese medicine for chronic diseases of EB virus positive people without canceration was implemented,and the significance of the management plan for its long-term curative effect was discussed,providing reference for clinical intervention and treatment of EB virus positive people,and also providing objective basis for the management of chronic diseases of traditional Chinese medicine,so as to achieve the purpose of reducing EB virus level or turning negative,and reducing the incidence rate of nasopharyngeal carcinoma through early intervention of traditional Chinese medicine.MethodsNon-nasopharyngeal carcinoma patients with EB virus antibody positive detected in Guangdong Provincial Hospital of Traditional Chinese Medicine from January 2017 to January 2018 were collected.According to the patient,s knowledge and consent,personal information of the population is collected and a database is established,including personal information such as gender,age,race,ancestral home,place of residence,family history,environmental exposure,eating habits,bad habits,education level,physical exercise,etc.As well as the results of TCM constitution recognition.Subjects were randomly divided into two groups.The experimental group adopted a systematic TCM chronic disease management scheme,while the control group adopted a TCM chronic disease management scheme except herbal extracts.The treatment period was 1 year.The EB virus before admission,3 months and 1 year later were reviewed.After the observation,the data were entered and corrected by double entry method,and analyzed by IBM SPSS statistics V24.0.0 software.Results1.In the main TCM constitutions of 56 EB virus positive subjects collected in this study,qi deficiency constitution(48.21%)and yang deficiency constitution(17.86%)are the most common.In 36 patients with other syndromes,phlegm-dampness constitution(20.00%),qi stagnation constitution(14.29%),damp heat constitution(20.00%)and congestion constitution(14.29%)are more common.2.The changes of level,OD value and negative conversion rate about the EBV antibody detected before,3 months and 1 year after the two groups of patients were enrolled in the group were compared.after statistical analysis,the decline level and OD value of EBV in the experimental group were better than those in the control group 3 months and 1 year after the patients were enrolled in the group,with statistical significance(P<0.05).The negative conversion rate in the experimental group was higher than that in the control group one year after admission,with statistical significance(P<0.05).Conclusion1.Qi deficiency constitution and yang deficiency constitution may be the main TCM constitutions of EB virus infection positive populatiort,while phlegm dampness constitution,qi stagnation constitution,damp heat constitution and blood stasis constitution may be the common TCM constitutions and combined constitutions of EB virus infection positive population.2.For EBV positive population,the implementation of TCM chronic disease management plan has certain influence on the decline of EBV level and the change of negative conversion rate.