Clinical Effects Of Different Surgical Treatments On Children With OSAHS And Their Effects On Children's Immune Function

BackgroundObstructive sleep apnea hyppnea syndrome(OSAHS)is a common otorhinolaryngological disease,and the prevalence of this disease in children is increasing year by year.Relevant studies have shown that OSAHS not only affects the growth and intellectual development of children,but also affects many systems and organs,causing a variety of complications.Hypertrophy of tonsils and adenoids is the main cause of this disease,so adenoidectomy and tonsillectomy are the first choice of treatment for children with OSAHS.With the increasing application of low temperature plasma(LTP)system in the medical field,the curative effect of its auxiliary surgical treatment needs to be studied and discussed.In addition,tonsils and adenoids as lymphatic organs in the human body participate in the human immune response,children adenoids and tonsillectomy on immune function and how to choose the appropriate surgical method,there is no clear conclusion,for a long time,doctors have been the focus of debate.ObjectiveObjective to investigate the clinical effect of plasma assisted tonsillectomy and adenoidectomy on children with OSAHS,and the changes of their postoperative immune function.MethodEighty OSAHS children who met the diagnostic criteria were selected and divided into observation groupand control group Low temperature plasma assisted bilateral tonsillectomy and adenoidectomy were performed in the observation group,while adenoidectomy and bilateral tonsillectomy were performed in the control group.1.Intraoperative blood loss,pain score and postoperative white membrane loss time of the two groups were recorded,and the clinical efficacy of the two operations was compared.2.Peripheral blood samples of all children were collected 1 day before surgery and 3 months after surgery,and immunoglobulin,lymphocyte subsets and NK cells were detected.Result1.There were statistically significant differences between the two groups in intraoperative blood loss,postoperative pain assessment 48 hours after surgery,and postoperative white film shedding time between the two groups and the control group(P<0.01).2.Comparison of IgA,IgG and IgM in the same period between the observation group and the control group showed no statistical difference(P>0.05).After surgery,there was no significant difference in immunoglobulin levels between the observation group and the control group(P>0.05).3.The difference in lymphocyte subsets was not statistically significantin between observation group and control groupbetween(P>0.05).In the two groups,there were no significant differences in percentage of CD4+,CD4+/CD8+,percentage of CD8+ and percentage of NK cells after surgery compared with that before surgery(P>0.05).Conclusion1.Low-temperature plasma-assisted adenoidectomy and tonsillectomy can reduce intraoperative blood loss,effectively relieve pain of children and prolong postoperative white film shedding time.2.Surgical treatment has no adverse effect on the immune function for children with OSAHS,and this conclusion is not changed by different surgical methods.