Clinical Observation Of Chaihu Plus Keeling-oyster Decoction In The Treatment Of Coronary Heart Disease With Mild To Moderate Depression

Objective: To observe the clinical effect of bupleurum plus keel oyster soup in the treatment of coronary heart disease with mild to moderate depression,and to provide an effective method for the clinical treatment of this kind of disease.Methods: Select 60 patients with the research into the standard,were randomly assigned into the treatment group and control group,30 cases in treatment group on the basis of conventional western medicine treatment,and give priority to with radix bupleuri add keel oyster soup from Fried particles fang for treatment;The control group was given shugan jieyu capsule on the basis of conventional western medicine treatment,and the course of treatment was 4 weeks.The comparative treatment and clinical efficacy evaluation were conducted,and the changes of TCM syndrome scores,angina pectoris,electrocardiogram and Hamilton depression scale(HAMD)scores of the two groups were compared before and after treatment.Results: the TCM syndrome scores of the two groups were improved before and after treatment,and the treatment group was better than the control group,with a significant difference(P<0.05).In terms of ecg,angina attack and frequency,the treatment group was better than the control group with significant difference(P<0.05),and the HAMD depression scale score was improved.The treatment group was better than the control group with significant difference(P<0.05).There were no adverse reactions in the two groups.Conclusion: 1.Bupleurum plus keel oyster soup has a definite effect on the treatment of coronary heart disease with mild to moderate depression,and has a significant effect on improving the clinical syndromes of TCM in patients.2.Bupleurum and keel oyster soup can significantly improve the ecg myocardial ischemia of patients with coronary heart disease accompanied by mild to moderate depression,and improve the angina pectoris of patients.3.The addition and subtraction of bupleurum and keel oyster soup can improve the HAMD score and improve the depression state of patients with coronary heart disease with mild to moderate depression.