Results Of Electronic Rectum Colonoscopy Screening And Correlation Analysis On Risk Factors Of Colorectal Cancer In Physical Examination Population In A Certain Area

Objective Recently the incidence of colorectal cancer in China has been on the rise.According to a research on cancer in China in 2015,the incidence and mortality of colorectal cancer is expected to rank fifth in all malignant tumors.When diagnosed and treated early,the five-year survival rate of colorectal cancer is extremely high.However,the survival rate of terminal colorectal cancer is only 12%.Therefore,in order to better carry out the intervention plan for early screening and prevention of colorectal cancer,this study initially analyzes the situation of people who received electronic direct colonoscopy in a health management center in Hangzhou and their result of the questionnaire on risky factors of colorectal cancer,to understand the relationship between the occurrence of colorectal cancer and various high-risk factors and the effectiveness of the electronic straight colonoscopy,so as to provide a reference for early screening and prevention of colorectal cancer.Object and Methods object: A random sample of 1289 patients who underwent electronic direct colonoscopy at a health management center in Hangzhou from May to May 2017 to May 2018.The abandoned and incomplete or damaged 7 questionnaires are excluded.Therefore,the number of participants is 1282,including 827 males(64.51%)and 455 female subjects(35.49%).The age range is 22-78 years old.The average age is(47.9±10.3)years old..methods: Strictly control the operation level and operation procedure of the medical examiner for electronic direct colonoscopy.Ask for professionals to assist the examinees to fill out the risky factor questionnaires,and record the status of the participants,including name,gender,operation date,height(cm),weight(kg),diastolic blood pressure(dp),systolic blood pressure(sp)and high-risk factors like living behaviors such as smoking,drinking,eating habits and preferences,medication history,bowel habits,stool characteristics,sedentary habits,clinical symptoms.The data were analyzed and sorted by Excel2010,then entered and checked by the medical examiners and the questionnaires entry staffs.The data are described and processed by SPSS20.0 software.The ?~2 test was used for comparison between groups.The correlation analysis of high-risk factors was performed by two-class logistic regression.The statistical results were statistically significant when P<0.05.Results A total of 1282 subjects who underwent the electronic direct colonoscopy and filled risk factor questionnaires were selected in the study,including 827 male subjects(64.51%)and 455 female subjects(35.49%).The age range is from 22 years to 78 years old,with the average age being 47.9 ± 10.3)years old.594 cases(46.33%)were more than 50 years old,and 688 cases(53.67%)were under 50 years old.Among them,the number of people between the age of 50 and 60 is 423,which ranks the highest and accounts for 32.30% of the total.According to the X~2 analysis of the data,the rate of abnormal results of positive detection of disease in male subjects was 25.74%(330/1282);in female subjects the rate was 18.17%(233/1282).Hence,the result is considered to be statistically grouped in gender,with a significant difference(X~2 = 5.81,P = 0.02).In the examined population,the age of 50 years old was a division.The positive detection rate of the <50-year-old group was 23.63%(303/1282),while the positive detection rate of the ?50-year-old group was 20.28%(260/1282).There was no statistically significant difference between the two(X~2=0.01,P=0.92).When analyzed the total cases detected as precancerous lesions(rectal neoplasms,rectal adenomas,rectal polyps,rectal polyps and anal canal polyps),14 male subjects(11.39%,14/1282)and 35 female subjects(35/12822.73%)were found.The total number of cases of precancerous lesions was also statistically different in gender stratification(X~2=73.242,P=0.000).The total number of cases of precancerous lesions was also statistically different between different age groups(X~2=102.551,P=0.000).As the result of Logistic regression analysis shows,hypertension(OR=1.702,P=0.011);overweight or obese patients(OR=1.538,P=0.028);daily drinking(OR=2.396,P=0.004);smoking under 5 cigarettes a day(OR=3.096,P=0.003),smoking between 5 to 10 cigarettes a day(OR=2.784,P=0.017),smoking over 10 cigarettes a day(OR=3.449,P=0.000);long-term use of drugs(OR=1.670,P=0.024);Long-term abdominal pain(OR=2.215,P=0.024);water-like defecation(OR=22.438,P=0.000)are all risk-factors for colorectal precancerous lesions.Conclusion The results of detection between different genders and age groups are different.The seven factors,including high blood pressure,overweight or obesity,drinking,smoking,taking drugs,abdominal pain,and fecal morphology are risk-factors for colorectal precancerous lesions.Therefore,it is necessary to pay attention to the early screening of colorectal cancer in people over 40 years old,especially in those high-risk groups,and this group should be urged to achieve annual/time healthy examinations.Health education and healthy knowledge promotion should be taught to healthy people.The intervention of smoking and drinking of the population are very important.Hence,health management workers should actively formulate intervention programs and take actions to decrease the smoking and drinking of both general population and high-risk groups.it is necessary for healthy people to control their blood pressure and reduce the use of unnecessary medicines such as diet pills and health care products.At the same time,attention should be paid to people's abdominal pain and abnormal fecal morphology.Regular physical examinations should be taken to prevent the occurrence of diseases.It is believed that the electron direct colonoscopy is effective in screening colorectal cancer in the current general population health examination.