| Objective: Analysis of Colorectal cancer screening situation of residents in Qiao Kou district of wuhan.To explore the relationship between various kinds of risk factors,including living environment,and incidence of colorectal cancer(CRC).Method: Quantitative risk factors assessment questionnaire were used to screen at the beginning,then positive patients were screened by colonoscopies for community resident population which are between the ages of 40 and 74 in Qiao Kou district of wuhan,from July,2014 to December,2016.The diagnosis and prognosis of all lesions were determined by colonoscopy and pathological results.the questionnaire data and colonoscopy results were collected and summarized.SPSS17.0 software was used to analyze the detection rate of various intestinal diseases and analyze the relationship between various risk factors and incidence of colorectal cancer.Result: The number of preliminary screening was 6,817,and the number of questionnaire positive was 2012,while the initial screening positive rate was 29.5%(2012/6817).In the early screening crowd,the initial screening positive rate in the age group under 60 was 19.2%(1311/6817),the initial screening positive rate in the age group above 60 years was 10.3%(701/6817).The initial screening positive rate of the questionnaire in the age group under 60 was significantly higher than that in the age group above 60 years(P=0.004).The number of colonoscopies in high-risk groups was 1992.A total of 515 cases were detected,the detection rate of colonoscopy was 25.9%,including colorectal cancer detection rate was 3.5%(70/1992),57 cases of adenoma(2.9%),357 cases of non-adenomatous polyp(17.9%),31 cases of ulcerative colitis(1.6%).In 515 colorectal lesions,detection rate of male was 14.7 %(293/1992),and women was 11.1%(222/1992).The detection rate of colorectal lesions of male were higher than that of women(P<0.05).In the groups of 40-49,50-59,60-69 and 70-74,The detection rate of colorectal lesions was highest in the 50-59 year group(10.1%,201/1992),The 60-69 year group was the second(8.8%,176/1992),and the 70-74 year group was the lowest(2.2%,42/1992).Further analysis of CRC population showed that males accounted for 2.1%(42/1992)and women 1.4%(28/1992),the detection rate of male was higher than that of female(P=0.022).According to the stratification analysis of age group,the prevalence rate of the group aged 60-69 was the highest,accounting for 1.7%(34/1992),followed by the 50-59 group(0.8%,16/1992),and the lowest in the 40-49 group(0.4%,8/1992).Further stratification analysis shows that among people under 60 years of age,CRC detection rate of male was higher than that of female(0.9% vs 0.3%),and the difference was statistically significant(P<0.05).However,there was no statistical difference between male and female in CRC detection after age 60(1.2% vs 1.0%,P>0.05).According to the detection site,the proportion(70%)of the distal CRC was significantly higher than that of the proximal CRC(30%).Analysis of risk factors showed that the CRC detection rate was the highest in the people who have a history of mucous blood,and CRC family history of first-degree relatives(P<0.05).Conclusion: Preliminary screening of questionnaires combined with colonoscopy is an effective method for CRC community screening.People aged 50-69 are the main targets for screening,In particular,Screening should be focused on men and postmenopausal women,especially those with mucous blood stool history,and CRC family history of first-degree relatives. |
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