| Objective To explore the value of MRI in the differential diagnosis of mass-forming chronic pancreatitis?MFCP?and pancreatic cancer?PC?.Methods MRI data of patients with MFCP and PC who were confirmed by pathology or followed up for more than one year in our hospital from June 1,2016 to July 31,2018were retrospective analyzed,including 19 cases of MFCP whose mean age was?53.4±14.4?years old,36 cases of PC whose average age was?58.1±12.0?years old.Thirty cases of normal pancreas examined at the same time were enrolled as normal control,whose average age was?51.7±18.4?years old.All patients underwent routine MRI examination and DWI scanning,and the images were imported into the post-processing software to analyze the signal characteristics of the diseased tissue and the normal pancreas,and compare the ADC values.The combined predictors were calculated using logistic regression equations and the diagnostic sensitivity and specificity of all results were compared.Results The mean ADC value of the MFCP group was?1.41±0.25?×10-3mm2/s,which was higher than that of the PC group[?1.13±0.11?×10-3mm2/s,P<0.05];lower than the normal control group[?1.50±0.27?×10-3mm2/s,P<0.05].In the plain T2WI,enhanced scanning arterial phase,and enhanced scanning portal phase,the signal characteristics of the lesions were statistically different?P<0.05?,ADC sensitivity was 82.6%and specificity was 77.8%for identifying pancreatitis and pancreatic cancer.The spot type signal onT2WI,the target ring type enhancement on arterial phase,and ADC value were selected as the combined predictive factor.The sensitivity of the combined predictive factor was 86.9%and the specificity was 88.9%,which was better than any single identification method.Conclusion Multi-sequence combination of MRI is one of the effective methods for identifying MFCP and PC,and has reference significance for clinical diagnosis. |
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