| Objective:The aim of this study was to compare the effects of the aerobic combined resistance exercise and the same dose of aerobic exercise on Cardiorespiratory Fitness,glycolipid metabolism,body composition,QOL scores,and the risk of Cardiovascular Disease in type 2 diabetes.Methods:We randomized 224 participants with type 2 diabetes mellitus in parallel to 6 months of aerobic exercise group(n=76),aerobic combined resistance exercise group(n=73)and control group(n=75).Before exercise,all patients received diet education.The aerobic exercise group performed moderate exercise three times a week for 50 minutes and continuous exercise for 6 months.The aerobic combined resistance exercise group performed moderate aerobic exercise for 50 minutes and,50 minutes each time,continuous exercise for 6 months;the control group kept the original lifestyle unchanged.Results:A total of 224 patients participated in the study,209 patients completed the study and performed data analysis.There were 72 patients in the aerobic exercise group,69 in the aerobic combined resistance exercise group,and 68 in the control group.Before the intervention,the baseline data of the three groups were comparable(p>0.05),After 6 months intervention,Mets(P<0.001),muscle mass(P<0.001)3 glycosylated hemoglobin(P<0.001),fasting blood glucose(P<0.001),HOMA2-p(P=0.041)were observed among the three groups.Statistical significance was statistically significant in body weight(P=0.012),BMI(P=0.009),HDL-C(P<0.001),LDL-C(P<0.001),and QOL score(P<0.001).There was no significant difference in glycosylated hemoglobin(P=0.067)and fasting blood glucose(P=0.384)between aerobic and aerobic combined resistance exercise,but both were significantly better than the control group;On the other hand,there was no statistical difference between the aerobic exercise group and the aerobic combined resistance exercise group,but from the perspective of improvement,the aerobic combined resistance exercise group was higher than the aerobic exercise group.With group,the 6-month aerobic combination resistance exercise can effectively increase muscle mass,ratio waist to hip(P=0.036),increase high-density lipoprotein level(P<0.001),increase aerobic Metabolic capacity and metropolitan value(P<0.001)decreased glycated hemoglobin(P<0.001),fasting blood glucose(P<0.001),and postprandial 2 h blood glucose(P?0.002),decreased TC(P=0.001),and LDL-C level(P?0.001),improved Framingham risk score(P?0.032)and annual CHD10 risk(P?0.046);6 months aerobic exercise reduced waist circumference(P?0.001)and waist to hip ratio(P= 0.036),HDL-C level(P?0.030),Mets(P<0.001),HbAlc value(P<0.001),fasting blood glucose(P=0.007),Conclusions:1.Compared to control group,6 months of aerobic and aerobic combined resistance exercise can improve Mets significantly;2.Compared to control group,both aerobic and aerobic combined resistance exercise can improve HDL-C level significantly;3.Compared to control group,6 months of aerobic and aerobic combined resistance exercise can effectively improve HbAlc and FBG,and the aerobic combined resistance exercise was better than aerobic exercise;4.Compared to control group,6 months of aerobic and aerobic combined resistance exercise can improve the quality of life scores;5.Compared to control group,6 months of aerobic and aerobic combined resistance exercisecan improved the risk of FRS and coronary heart disease(CHD);6.Comparison to aerobic exercise group,aerobic combined resistance exercise can increase muscle mass significantly.7.Within group,6 months of aerobic combined resistance exercise can reduce TC?LDL-C levels;8.Within group,6 months of aerobic exercise can effectively reduce the waist circumference. |
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