Clinical Study Of Cystatin And High-sensitivity C-reactive Protein Levels In Patients With Depression After Coronary Stent Implantation

purpose:To investigate the relationship between depression and plasma high-sensitivity C-reactive protein and cystatin levels after coronary stent implantation.method:According to the inclusion criteria and exclusion criteria of this study,92 patients admitted to the Department of Cardiology of the Second Hospital of Jilin University from February 20,2018 to January 2019 were enrolled.According to the SDS scoring criteria,they were divided into a non-depressed group(n = 47)and a depression group(n = 45),and hs-CRP and CysC values were determined in the two groups of patients.General data of the two groups of patients and hs-CRP and CysC were statistically analyzed using SPSS 22.0.result:The general condition(age,sex,body mass index,smoking and drinking history,hypertension,diabetes,combined with peripheral vascular disease,taking statin lipid-lowering drugs,taking beta blockers)were not statistically significant.(P>0.05).An independent sample t-test between the two groups showed that serum hs-CRP and CysC levels were significantly higher in the depression group than in the non-depressed group,and hs-CRP and CysC levels were positively correlated with SDS scores in depressed patients(0.457,0.273).in conclusion:1.The levels of hs-CRP and CysC in patients with depression after coronary intervention were significantly higher than those in nondepressed group.2.In patients with depression,as the SDS score increased,the levels of hs-CRP and CysC increased accordingly.