Comparative Analysis Of Clinical Characteristics Of Hyperlipidemic Acute Pancreatitis And Acute Biliary Pancreatitis

Objective:By comparing the clinical data of hyperlipidemic acute pancreatitis and acute biliary pancreatitis,the similarities and differences of their clinical characteristics were analyzed,which provided theoretical basis for the clinical diagnosis and treatment of the two diseases.Methods:The clinical data of 40 cases of HLAP and 40 cases of ABP treated in the Second Hospital of Jilin University from January 2016 to June2018 were retrospectively analyzed.Clinical data include general data,laboratory indicators,imaging data,concomitant diseases,complications,treatment and recovery,and severity of the disease.All clinical data were processed by statistical software,and the results were compared and analyzed.Result:1.The age of onset in HLAP group was significantly lower than that in ABP group?P<0.05?.The proportion of male patients in HLAP group was significantly higher than that in ABP group.The BMI in HLAP group was significantly higher than that in ABP group?P<0.05?.There was no statistical difference in hospitalization days?P>0.05?.2.The levels of TG,TC in HLAP group were significantly higher than those in ABP group?P<0.05?,the level of LDL-C is on the contrary(?P<0.05?,but HDL-C had no statistical difference?P>0.05?.3.The levels of WBC and HCT in HLAP group were significantly higher than those in ABP group?P<0.05?,and NEUT%had no statistical difference?P>0.05?.4.The levels of ALT,AST,TBIL,DBIL and ALP in the ABP group were significantly higher than those in the HLAP group?P<0.05?;the levels of AMY in the HLAP group were significantly lower than those in the ABP group?P<0.05?,the UAMY had no statistical difference?P>0.05?;the levels of GLU in the HLAP group were significantly higher than those in the HLAP group?P<0.05?,and CREA,BUN,Ca²⁺had no statistical difference?P>0.05?.5.There were more diabetes mellitus and fatty liver in HLAP group than in ABP group?P<0.05?.6.The proportion of abnormal liver function in HLAP group was significantly lower than that in ABP group?P<0.05?.There was no statistical difference in the incidence of pancreatic necrosis,pancreatic pseudocyst,pleural effusion,peritoneal effusion,cardiac insufficiency,kidney dysfunction,ARDS,MODS between the two groups?P>0.05?.7.The proportion of MAP in ABP group was higher than that in HLAP group,but the proportion of MSAP and SAP in ABP group was lower than that in HLAP group.There was statistical difference in severity classification of pancreatitis between the two groups?P<0.05?;Ranson score in HLAP group was higher than that in ABP group?P<0.05?;there was no statistical difference in MCTSI score between the two groups?P>0.05?.8.The recurrence rate of HLAP group was higher than that of ABP group?P<0.05?.There was no statistical difference in operation and mortality between the two groups?P>0.05?.Conclusion:1.The age of onset of HLAP was lower than that of ABP.Male patients with higher BMI were more likely to have HLAP.2.The level of TG in HLAP patients was significantly higher than that in ABP patients,and there was lipid metabolism disorder,which required lipid-lowering therapy,and plasma exchange therapy in severe cases.3.ABP patients are more likely to have abnormal liver function than HLAP patients.4.AMY in HLAP patients can be normal or slightly elevated.For suspected cases of AP,we should combine the results of blood lipid and imaging diagnosis to avoid missed diagnosis and misdiagnosis.5.The proportion of diabetes mellitus and fatty liver in patients with HLAP is higher than that in patients with ABP.Patients with diabetes mellitus and fatty liver should pay attention to controlling blood sugar and lipid to prevent the occurrence of HLAP.6.Compared with ABP,HLAP is more likely to progress to MSAP and SAP,and the recurrence rate of HLAP is higher.Patients who have just recovered from HLAP should strictly control blood lipid to prevent recurrence of HLAP.