Significance Of ?-GT And ALP In Pathological Jaundice Of Late Preterm Infant

Objective:The correlation between GT and ALP levels and pathological jaundice in late preterm infant is a predictor of pathological jaundice in late preterm infant.Methods: All 68 late preterm infants were admitted to NICU of our hospital from September 2018 to February 2019.40 late preterm infants with pathological jaundice were selected as the case group.The control group selected 28 cases of late preterm infants with physiological jaundice in the same period.All late term infants' gender,weight,gestational age,birth pattern,total serum bilirubin(TSB)levels at 24 h after birth and 7 days after birth,serum ?-glutamyltransferase(?-GT)levels at 24 h after birth and 7days after birth and serum alkaline phosphatase(ALP)levels at 24 h after birth and 7 days after birth were analyzed.The correlation between TSB and ?-GT and ALP was analyzed separately.Results: A total of 68 preterm infants were included in the study,including 42 male infants and 26 female infants.After the age of birth,the preterm infants at the 34 th,35th,and 36 th week of gestational age were 18 Name,26 and 24 people.According to the mother's mode of delivery,20 of them were born,and 48 were cesarean section.The average birth weight of 68 preterm infants was 2440.88 ± 427.71 g.There were 40 late preterm infants with pathological jaundice and 28 with physiological jaundice.TSB in the pathological group were significantly higher than those in the control group at 7 days.There was a statistically significant difference in TSB between the two groups(P<0.05).TSB levels and serum ?-GT levels and ALP at 24 hours after birth and 7 days after birth.There was no significant correlation between the levels(P>0.05).Conclusion: 1.Diagnosis of neonatal pathological jaundice usually depends on the serum TSB and Tc B.The dynamic changes of serum ?-GT and ALP could not be used as indicators of pathological jaundice.2.There was no significant correlation between serum levels of gamma-GT and ALP and serum levels of TSB,suggesting that gamma-GT and ALP were not enough as auxiliary diagnostic indicators for pathological jaundice.