Acupuncture Combined With Moxibustion For Treating Knee Osteoarthritis Of Liver And Kidney Deficiency Clinical Study On The Time-effect Of Balance

Objective To observe the clinical efficacy,onset time and long-term curative effect of balance acupuncture combined with moxibustion for treating knee osteoarthritis of liver and kidney deficiency,so as to seek a clinical treatment for rapid analgesia and stable effect method.Methods From March 2018 to December 2018,60 patients who were diagnosed as KOA and met the inclusion criteria at the Acupuncture Clinic and Inpatient Department of the First Affiliated Hospital of Guangxi University of Traditional Chinese Medicine will be randomly selected according to their order of treatment.Patients were randomly assigned to the treatment group(balanced acupuncture combined with moxibustion group)and the control group(oral celecoxib capsule group),30 cases in each group.The treatment group was treated with acupuncture balance acupuncture knee pain point combined with moxibustion Guanyuan point and Yongquan point.One acupuncture per day,7 treatments for one course of treatment,1 day of treatment,4 courses of continuous treatment;Celecoxib capsules,200 mg / time,once / d,7 treatments for 1 course of treatment,4 courses of continuous treatment.VAS score,WOMAC scores(including pain,stiffness,daily activity)were used as observation indicators,and the two groups were different at different time points(pre-treatment,treatment 5 min,treatment 30 min,treatment 1 week,treatment 2 weeks,treatment 4 weeks).At the time of follow-up,the treatment was evaluated;the TCM syndrome score table was used to evaluate the overall efficacy of the liver and kidney deficiency syndrome before and after treatment;and the number of knee pain recurrences in the two groups was counted at follow-up.The recurrence rate was observed to assess long-term efficacy.The data obtained were analyzed by SPSS22.0 statistical software.Results(1)There was no statistically significant difference(P>0.05)in the general data of sex,age and course of the two groups.(2)Comparison within the treatment group: The VAS score and WOMAC scores(including pain,stiffness,and daily activity)at each time point in the treatment group were lower than those before treatment,and the difference was statistically significant(P<0.05);Comparison of VAS scores and WOMAC scores(including pain,stiffness,daily activity)between various time points(5 min,30 min,1 week,2 weeks,4 weeks,and 3 months follow-up)The difference was statistically significant(P<0.05).(3)Comparison within the control group: There was no significant difference in the VAS score and WOMAC scores(including pain,stiffness,and daily activity)between the control group and the control group(P>0.05).The VAS score and WOMAC scores(including pain,stiffness,and daily activity)were lower than those before treatment(P<0.05);all time points after treatment(treatment 5 min,30 min,1 week,2 weeks,4 weeks and Comparison of VAS scores and WOMAC scores(including pain,stiffness,and daily activity)between the 3 months follow-up period,except for the difference between the follow-up and the 4 weeks of treatment,was not statistically significant(P> 0.05),the differences between the remaining time points were statistically significant(P<0.05).(4)Evaluation of the curative effect of TCM syndrome: The total effective rate of the treatment group was 96.7 %,and that of the control group was 63.3 %.The difference between the two groups was statistically significant(P<0.05).(5)There was a statistically significant difference in the recurrence rate of knee joint pain between the two groups: 13.3 % in the treatment group and43.3 % in the control group(P<0.05).Conclusion(1)Both the balanced acupuncture combined with moxibustion and oral celecoxib capsules can improve the pain,stiffness and daily activities of patients with liver and kidney deficiency type KOA.(2)The effect of balance acupuncture combined with moxibustion on KOA of liver and kidney deficiency type is significantly better than that of oral celecoxib capsule,and the curative effect is more obvious with the prolongation of treatment time.(3)Balanced acupuncture combined with moxibustion for the treatment of liver and kidney deficiency type KOA has a clear immediate analgesic effect and good long-term efficacy.