Association Between 24h Urinary Sodium Excretion And Blood Pressure In Patients With Primary Hypertension

Objective: To investigate the relationship between 24 h urinary sodium excretion and blood pressure in patients with essential hypertension.Methods:Selecting 195 adults with essential hypertension,and sodium intake was evaluated by 24 h urinary sodium excretion.The selected patients were divided into low urinary sodium group(n=47),intermediate urinary sodium group(n=84),and high urinary sodium group(n=64).The office blood pressure and the 24-hour ambulatory blood pressure level was measured.The24-hour ambulatory blood pressure levels included 24-hour mean systolicblood pressure,24-hour mean diastolic blood pressure,mean daytime systolic blood pressure,mean daytime diastolic blood pressure,mean nighttime systolic blood pressure and mean nighttime diastolic blood pressure.We analyzed the correlation between24 h urinary sodium excretion and blood pressure.Results: The difference of 24 hDBP,dDBP,nDBP and office DBP in the three groups was statistically significant(P < 0.05).The 24-hour urinary sodium excretion was the influencing factors of 24 hSBP,24hDBP,dSBP,dDBP,nSBP and nDBP.At the same time,the effect of BMI on 24 hSBP,dSBP and nSBP was statistically significant.The 24-hour urinary potassium excretion was inversely related to 24 hSBP,dSBP and nSBP.Age is inversely related to 24 hDBP,dDBP,and nDBP.(P<0.05).Conclusion:There is a positive correlation between 24-hour urinary sodium excretion and blood pressure level in patients with hypertension.Controlling 24-hour urinary sodium excretion in patients with hypertension has important clinical significance in controlling blood pressure level.