| Objective: To observe the effect of Yi qi huatan qu yu decoction,Six word strategy breathing exercises,six words breathing exercises combined with Yi qi huatan qu yu decoction,and to evaluate the effect and safety of the patients in the stable stage of the chronic obstructive pulmonary disease(the severity grade belongs to the middle and severe severity and the TCM syndrome type belongs to the lung spleen qi deficiency and phlegm stasis type),and the prevention and control of the slow resistance lung.Provide new treatment ideas and theoretical basis.Methods: 120 patients who met the inclusion criteria were randomly divided into four groups: A,B,C and D.Group A was used as the routine group and treated with tiotropium bromide inhalant;group B was treated with tiotropium bromide inhalant and Yiqi Huatan Removing Stasis Decoction;group C was breathing exercises group,tiotropium bromide inhalation and six words breathing exercises were given,and group D was combined with tiotropium bromide,Yiqi Huatan and Stasis Decoction and six words.After 6 months,the effects of main symptoms,TCM syndrome score,lung function,quality of life(CAT score),respiratory difficulty(mMRC score),exercise endurance(6MWD),blood routine,liver and kidney function,routine and electrocardiographic changes were observed to evaluate the effectiveness and safety of the patients after 6 months.Sex.Results: the main evaluation criteria: efficacy evaluation: group D was the best;B and C two groups had different degrees of improvement,but the difference was not statistically significant;the three groups were better than A group.Secondary evaluation criteria: pulmonary function change: the four groups were improved after treatment,the difference was statistically significant(P<0.05),group D was the best,A,B,C three groups were different,but there was no statistical difference between each other.Quality of life: four groups of patients after the treatment of CAT scores were reduced,the difference was statistically significant(P<0.05),the D group was the best,the B group,the C group,three groups were better than the A group.The degree of dyspnea: the levels of mMRC in the four groups were reduced after treatment.The difference was statistically significant(P<0.05),and the best in group D.Although the three groups were different,there was no statistical difference between the groups of A,B and C.Exercise endurance: four groups of patients after treatment increased 6MWD,the difference was statistically significant(P<0.05),D group was the best,C group,B group,C group was better than the B group,three groups were better than the A group.TCM syndrome score: four groups of patients after treatment in the lung qi deficiency syndrome,spleen qi deficiency syndrome,blood stasis syndrome,phlegm syndrome scores were reduced,A group difference was not statistically significant,B,C,D group differences were statistically significant,D group was the best,B,C group,three groups were better than the A group.Safety assessment: tachycardia was found in 2 patients in group A after treatment,and Betaloc was improved.There were no security problems in the three groups of B,C and D,Conclusion:(1)six words and breathing exercises combinedYi qi huatan qu yu decoction can relieve the symptoms of cough,expectoration and suffocating,improve the syndrome of Chinese medicine,relieve the difficulty of breathing,improve the exercise endurance and the quality of life,and improve the lung function of the patients.Yi qi huatan qu yu decoction,six character breathing exercises.(2)the six words breathing exercises,Yi qi huatan qu yu decoction can improve the symptoms of the patients(lung spleen qi deficiency,phlegm stasis internal resistance),improve the patient's sports endurance,improve the patient's quality of life,improve the syndrome of traditional Chinese medicine,and improve the exercise endurance of the patients,and the six character formula is superior to the Yiqi Huatan Removing Stasis Decoction.(3)six word breathing exercises and Yi qi huatan qu yu decoction have good safety. |
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