A Clinical Study Of Treating Insomnia Based On The Theory Of Ascending Descending Exiting And Entering

Objective:Based on the guidance of the ascending,descending,exiting and entering theory,treating insomnia with Banxiaxiexin Decoction Modified and observing clinical efficacy to verify the feasibility of adjusting the ascending,descending,exiting and entering of qi to treat insomnia,explore the mechanism of the insomnia caused by the turbulence of qi and Provide new ideas for clinical treatment of insomniaMethod:60 insomnia patients meeting the inclusion criteria were randomly divided into treatment group and control group,with 30 cases in each group.The treatment group was treated with Banxiaxiexin Decoction Modified and the control group was treated with alprazolam.Both groups were treated for 4 weeks as one course of treatment.PSQI scale,TCM symptom scale,mental health scores,clinical efficacy and drug safety were taken as observation index to evaluate the clinical efficacy of Banxiaxiexin Decoction Modified in treating insomnia objectively and systematically.Result: PSQI scale:There was a significant difference between the treatment group and the control group before and after treatment(P<0.01).The scores of each item of the PSQI scale fall significantly in both treatment group and control group.There was no statistical difference in each item of the PSQI scale before treatment(P>0.05).There was a statistical difference in sleep quality and daytime dysfunction between the two groups after treatment(P<0.05).The treatment group was superior to the control group in improving sleep quality and daytime dysfunction;there was no statistical difference in time for falling asleep,sleeping time,sleep efficiency,sleep disorders,and total score(P>0.05).The two groups have the same efficacy.In the TCM symptoms scale,there was a significant difference between the treatment group and the control group before and after treatment(P<0.01).Both groups were able to significantly improve TCM symptoms.There was no statistical difference in each item of TCM symptom scale before treatment(P>0.05).After treatment,the two groups were statistically different in terms of dream-disturbed sleep,tiredness and lethargy and feeling depressed(P<0.05),the treatment group was better than the control group in improving dream-disturbed sleep,tiredness and lethargy and feeling depressed.There was no statistical difference in difficulty falling asleep,forgetfulness,loss of appetite(P>0.05),The two groups have the same efficacy.In terms of mental health scores,there was a significant difference between the treatment group and the control group before and after treatment(P<0.01).The scores of the mental health rise significantly in both treatment group and control group.There was no statistical difference before treatment(P>0.05),there was a statistical difference between the two groups after treatment(P<0.05).The effect of the treatment group was better than that of the control group.Clinical efficacy: The effective rate of clinical curative effect was 86.7% in the treatment group and 70.0% in the control group.There was a statistical difference in the rank sum test(P<0.05).The clinical efficacy of the treatment group was superior to that of the control group.During the course of treatment,no obvious adverse drug reactions occurred in the treatment group,and mild control of constipation occurred in the two control patients.Conclusion: Banxiaxiexin Decoction Modified can significantly improve the clinical symptoms of patients with insomnia,and it is feasible to treat unrelenting diseases by adjusting ascending,descending,exiting and entering of qi.