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The RTMS Study On Cognitive Function And Craving Of Patients With Methamphetamine Dependence

Posted on:2019-04-23Degree:MasterType:Thesis
Country:ChinaCandidate:J D FengFull Text:PDF
GTID:2404330572958868Subject:Mental Illness and Mental Health
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Objectives:Through Montreal cognitive assessment scale evaluation of cognitive function after repetitive transcranial magnetic stimulation treatment changes,through visual analog scale evaluation after repetitive transcranial magnetic stimulation treatment psychological desire to reduce the situation,then to explore repetitive transcranial magnetic stimulation of methamphetamine dependence on cognitive function and the influence of psychological craving.Methods:In the Diagnostic and Statistical Manual of mental illness-Fifth edition(DSM-V)diagnostic criteria of amphetamines stimulant use disorders MA dependent as the research object,according to the order by adopting the method of stratified random grouping,mild,moderate,severe selected 20 cases were randomly divided into experimental group and the control group after.The experimental group and control group 30 cases each.rTMS treatment,while control group received sham stimulation treatment,treatment of 4 weeks.For all subjects before and after therapy MoCA and VAS scale test,record MoCA and VAS score values and MoCA seven component values.Results:1.The results of MoCA1.1each group before and after treatment of MoCA comparisonThe experimental group and control group before and after treatment the total score value comparison has no obvious difference(P>0.05).Experimental group total score value increased after treatment,compared with before treatment differences statistically significant(P<0.01);Experimental group and control group before and after treatment of MoCA scores compared difference,the difference was statistically significant(P<0.05).MoCA breakdown value comparison,breakdown value has no obvious difference between groups before treatment(P>0.05).The experimental group after treatment in the visual space,pay attention to,delayed recall three disciplines in score was improved,the difference before and after treatment(P<0.01).Repetitive transcranial magnetic stimulation can increase methamphetamine dependence on visual space and execution,attention and delayed recall scores.The control group after treatment in the note item score higher than before treatment,there are differences before and after treatment(P<0.05).Methamphetamine dependent attention after the false stimulation treatment ability.Breakdown value comparison between the two groups after treatment,there are differences between the visual space and execution score(P<0.05),suggesting repetitive transcranial magnetic stimulation can improve the visual space of methamphetamine dependence and executive ability.1.2 MoCA percentage comparison before and after the treatment between groupsThe effective rate of 83%,controls effective rate was 83%.The experimental group than control group in high efficient,after statistics analysis,between the two groups was statistically difference(P<0.05),the results suggest methamphetamine dependence after treatment with repetitive transcranial magnetic stimulation effective cognitive functions are improved to a certain extent.1.3 The comparison of different severity curative effect between groupsMild effective rate of 60%,moderate effective rate was 60%,severe effective rate was 90%.Prompt repetitive transcranial magnetic stimulation of different severity of methamphetamine dependence is different curative effect,of moderate and severe dependence is more efficient.2.The results of VAS2.1 VAS results comparison between groupsThe experimental group and control group before treatment VAS score has no obvious difference(P>0.05);Difference of VAS scores before and after treatment between two groups of comparison,there are differences(P<0.01);Differences between experimental group comparing VAS scores before and after the treatment(P<0.01);The control group before and after treatment VAS score comparison differences(P<0.01).The experimental group after treatment VAS score with the lower score than before treatment(P<0.01);The experimental group after treatment VAS score lower than the control group(P<0.01);The control group after treatment VAS score with the lower score than before treatment(P<0.01).2.2 The comparison of VAS results in the experimental groupExperimental group different severity research object before and after treatment VAS score had no obvious difference(P>0.05);Before and after treatment comparison: mild,moderate,severe difference of VAS scores before and after treatment were different(P<0.01),with moderate and severe scores before and after difference was bigger.Conclusions:1.The high frequency rTMS can improve MA rely on visual space and execution,attention and delayed recall score,hint of methamphetamine dependence can improve the cognitive function;And dependent on different severity curative effect is different,the curative effect of moderate and severe dependence relatively mild rather than relying on more obvious improvement points rate growth.2.High frequency rTMS treatment after MA dependents,desire to reduce.Moderate and severe more dependent score difference before and after the treatment,prompt moderate and severe MA dependent than mild thirst reduce degree is more obvious.
Keywords/Search Tags:Repetitive Transcranial Magnetic Stimulation, Methamphetamine, Cognitive function, craving
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