Effects Of Protein-energy Wasting On Quality Of Life In Maintenance Hemodialysis Patients

Objective: To investigate the prevalence of Protein-Energy Wasting(PEW)and its effects on quality of life(QoL)in patients undergoing maintenance hemodialysis(MHD).Method: A total of 257 patients in 4 hospitals in Xinjiang Provience were included in this study.The Scored Patient-Generated Subjective Global Assessment(PG-SGA)was used as the diagnostic criteria for PEW.Based on the PG-SGA scores,they were divided into three groups: non-PEW group,mild to moderate PEW group and severe PEW group.Health-related quality of life(HRQoL)was assessed by the Short Form 36 Healfh Survey(SF-36).Results: The detection rate of PEW was 54.9%.With the severity of PEW,each SF-36 dimension scores decreased significantly.One-Way ANOVA showed that age,marriage,number of children,education level,family care,monthly income,health insurance,primary disease,and PEW were important factors affecting HRQoL of MHD patients(P<0.05).Multiple linear regression demonstrated that there were significant negative correlations between age,PEW and HRQoL of MHD patients(P <0.05).Conclusion: PEW is an important factor affecting the HRQoL of MHD patients.With the severity of PEW,HRQoL of MHD patients tends to decline.More Attention should be paid to the prevention and treatment of PEW in MHD patients.