A Clinical Study On The Epidemiology Of 424 Patients With Acute Poisoning

Objective To investigate the clinical data and epidemiological characteristics of acute poisoning patients in Huai'an City,Jiangsu Province,and to provide reference for clinical treatment of poisoning in the region.Methods A single-center,prospective case investigation method was used to collect and analyze the clinical data of acute poisoning patients who were admitted to the emergency medicine department of Huai'an First Hospital affiliated to Nanjing Medical University from June 2015 to May 2017,including gender,age,and occupation,the season of onset,the path and cause of poisoning,the name and type of poison,the time from poisoning to treatment,vital signs at admission,test results,emergency treatment,and outcome.Results A total of 424 cases of acute poisoning were collected,including 177 males and 247 females,with an average age of 44.8 years.The highest acute poisoning cases(25.7%)were in the 40-49 age group.Suicide was the most common cause of acute poisoning(76.7%),and the most common path of poisoning was oral poisoning(87.3%).Pesticide poisoning was the most common poisoning poison(59.9%),with a seasonal distribution.The proportion of pesticide poisoning peaked in August.The top three poisoned pesticide varieties were organic phosphorus(35.0%),paraquat(23.6%)and glyphosate.(8.7%).Gastric lavage was a common intervention for patients with oral poisoning(70.0%),and blood perfusion was the most commonly used method of blood purification(95.0%).The in-hospital mortality rate of acute poisoning patients was 2.4%,the out-of-hospital mortality rate of automatic discharge patients was 72.7%,and the overall mortality rate of acute poisoning patients was 11.8%.The top three poisoning mortality rates were paraquat(61.7%),aluminum phosphide(33.3%),and organic phosphorus(7.87%).Conclusion Acute poisoning in Huai'an City has its regional epidemiological characteristics.The incidence and mortality of acute pesticide poisoning,especially paraquat,organophosphate poisoning is high.The promotion of pesticide use supervision and hazard should be strengthened to help guide the prevention and treatment of acute poisoning in the region.