An Epidemiological Investigation And Analysis Of 807 Hospitalized Patients With Acute Poisoning

Objective: The objective was to analyse the general information , treatment Prognostic , etc of poisoning were, hospitalized in 2006 ~ 2010,then find out the intrinsic relation to improve the pathogenesis regularity understanding of hospitalized patients with acute poisoning for cure and control Acute poisoning.Methods: A retrospective study was performed to analyze 807 hospitalized patients with acute poisoning in the First Affiliated Hospital of Dalian Medical University from 2006 to 2010,hospitalization number, hospital department check-in distribution, hospitalization days, age and sex ratio, poisoning cause, poison types and months distribution, treatment methods ,prognosis and etc were also collected.Results: Number of hospitalized patients with acute poisoning overall shows ascendant trend, especially in 2010 the patients had rose 31% compared with 2009. The main department, which receive 70.01% patients with acute poisoning, is still emergency medicine. The median of hospital day of acute poisoning patients was 5 days,the Q1 was 3 days, the Q2 was 11days. The patient's age of onset range from 2~95 years old, the high-risk age was 20～59 years old and the ratio of male to female was 1:1.51. Patients were mainly composed by farmers, unemployed, workers, students and children. 26.42% of the patients were farms, 20.74% of the patients were unemployed. Acute poisoning patients who had no intention of contact, achieving to 56.51%, others were 49.96%.43.49% of patients were suicide. Poison were mainly composed by drugs, carbon monoxide and pesticides,drugs is the maximum occupation among these poison,achieving to 29.49%. The number of patients in the second half obviously higher than that in the first half. Poisoning had a peak in July and August. Pesticide poisoning, toadstools poisoning, sting injury and bite has obvious seasonal characteristics. Most of the diagnosis based on medical history. The laboratory tests were meaningful to diagnosis in 378 patients. Only 28 patients rely on laboratory diagnosis. The indications patients were given special effects antidotes and semeiologically support treatment. 72.69% indications patients had treat by hyperbaric oxygen and 57.91% indications patients had treat by blood purification. 83.52%patients had gotten better or recovered, 6.20% patients had given up treatment, and 10.29% patients died , paraquat poisoning cases is the maximum occupation among these deaths, achieving to 31.88%.Conclusion: The number of patients with acute poisoning increases year by year. This situation is very serious. Most of the patients were short-term hospitalization, and initial treatment is more important. To prevent poisoning occurred we should strengthen the high-risk patients with psychological counseling, propaganda education etc. Some acute poisoning, which had presented obvious seasonal characteristics, should be intervention by corresponding emergency measure. Most of the diagnosis based on medical history. The laboratory tests were meaningful to diagnosis and treatment. Blood purification, hyperbaric was assured curative effects. Basic-level medical workers should be to improve the understanding of hyperbaric oxygen and blood purification. So they inform the patient or their family to choose appropriate therapy. Because of acute poisoning mortality rate is high, prevention is more important. The government should strengthen drug and highly toxic pesticide regulatory work.