Investigation And Analysis Of Central Precocious Puberty In Female Children

Objective: To investigate the precocious puberty of female children,analyze the influencing factors of precocious puberty,and put forward preventive measures and suggestions,in order to provide favorable reference and guidance for the prevention and treatment of precocious puberty in female children.Methods: Selected from January 2015 to 2017 10 in our hospital growth and development clinics,child health clinic and inpatient admitted 187 cases of female precocious children and 200 normal children as the research object,the former as the precocious puberty group,the latter As a normal control group.The use of physical examination,laboratory analysis of the decisive maturity,and the use of self-made questionnaire survey of female children's basic information,birth status,diet,lifestyle,family economics and their precocious siblings,mother's pregnancy status,occupation,education,Lifestyle and menarche age,etc.,and single factor,logistic regression analysis.Results:(1)There was significant difference between the precocious puberty group and the normal group in height,weight,bone age,ovarian volume and uterine volume(P <0.05).(2)Age,BMI index,sleep time without light,nutrition status,eating habits,annual family income,mother's education level,maternal menarche age,precocious puberty in siblings,etc.in precocious group and normal group Compared with significant difference,with statistical significance(P <0.05).There were no significant differences in body weight at birth,height at birth,gestational age,parity,birth time,mother's reproductive age,mother's pre-pregnancy weight,mother's birth weight and other factors(P> 0.05).(3)Multivariate logistic regression analysis showed that maternal menarche age,taking nutritional products,maternal education,eating habits and BMI were the independent influencing factors of sexual precocity in female children.Conclusions:(1)The height,weight,bone age,ovarian volume and uterine volume of precocious female children are higher than those of normal female children.(2)Univariate analysis showed that the age,BMI index,turning on the lights,taking nutritional products,eating habits,family annual income,mother's education level,mother's age,sibling mild precocious puberty belongs to the sexual precocity factor.(3)Multivariate analysis showed that maternal menarche age,weight at birth,taking nutritional products,maternal education,dietary habits and BMI were independent influencing factors of sexual precocity in female children.(4)A grass-roots intervention system should be established to form a comprehensive prevention and control system for children's health development with a community-based fertility culture center,a street family planning center,and a district family planning center,providing dietary guidance,exercise guidance,and health guidance for women and children.So that they can form a healthy diet as soon as possible;women and children do not often drink and drink,do not eat health supplements,but eat more high-protein foods to avoid intake of hormone-rich foods or drugs,adjust bad eating habits.