| Purpose To investigate the incidence of simple renal cysts(SRCs)in health examination population in Shenzhen,to assess their clinical features,analyze relevant risk factors and natural course,and provide guidance for disease prevention,clinical treatment,and index monitoring.Materials and Methods: The subjects from the April to November 2017 Health Examination program at the Shenzhen Affiliated Hospital of Shenzhen City and the Sixth People's Hospital of Shenzhen City were selected as the study subjects,and the ultrasound examinations of patients who were routinely screened by 1000 physical examination personnel were included in this study.By recording the relevant data of the subjects,univariate and multivariate analyses were performed to assess the relationship between the results and the correlation analysis to analyze the degree of association between the SRC and the factors.Result 1.SRC detection: The study group consisted of 363 women(38%)and 637 men(63%),with an average age of 42.76 ± 10.89 years.A total of 77 patients(7.7%)were diagnosed with SRC.The overall incidence of simple cysts was 7.7%(77/1000).There were a total of 123 cysts in these 77 patients.The average maximum diameter of renal cysts was 27.86 mm with a range of 5-66 mm.The average number of cysts per individual was 2.13 cysts.The isolated renal cyst was found in most patients(63.6%).Among polycystic patients,3.9% had more than 5 cysts.Through the analysis of the test results,we can see that the incidence of SRC increased with age,SRC patients were significantly older than those without cysts(P <0.01).When the cohort was classified by age group,the incidence rate among those under 40 years old was 2.7%,the incidence rate was between 40-60 years old was 10%,and the incidence rate was 26.9% for people over 60 years old,the difference was statistically significant(P<0.01).In patients with renal cysts,statistical analysis showed a significant positive correlation with the number of cysts with age(P<0.05).Among the patients who detected SRC,the proportion of male patients was found to be 94.8%.In our study population,11.45% of men and 1.10% of women observed SRC.Therefore,the male-female ratio is 10.41.The incidence of male SRC was higher,and the difference was statistically significant(P<0.01).2.SRC-related factors: A total of 55 subjects(5.5%)had a history/diagnosis of hypertension,and 98 subjects(9.6%)had a history/diagnosis of diabetes.The average total cholesterol level was 195.14 ± 40.04 mg/d L.Urinalysis revealed microscopic hematuria in 5% of the subjects.The mean serum creatinine was 0.76 ± 0.17 mg/d L.The analysis showed that the age,male rate,mean serum creatinine value,and BMI were significantly higher in the SRC group than in the non-SRC group.Further multivariate logistic regression analysis showed that age,male gender,and hypertension were significant independent predictors of the presence of renal cysts(P <0.001,P = 0.001,P <0.01,respectively).The BMI and total cholesterol levels,the history and diagnosis of diabetes,and the incidence of hyperglycemia were not statistically significant in individuals with or without renal cysts.(P >0.05)... |
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