The Influence On The Expression Of Bcl-2 And Bax After By Sdiuom ?-aescin To The Hurt Of Retinal Ischemia-reperfusion On Rats

Objective:In order to inveatigate the protective effect of sdiuom P-aescin to the hurt of RIR on rats.Methods:TO build the animal model of RIR through the method of anterior chanber perfusion pressure,then to observe the change of retinal tissure structure by the microscope after dealing with Hematein Eooin Staining(HE stain),try to learn the regularity of expression and change of Bcl-2 and Bax in eye retina of operated rats.Rats of RIR were intervented by adivom?-aescin,and to compare the change of expression of these true factors.Try to compare the difference of these true fartors among control group interventd group and normal group.Results:The rat retina could be driven into cacular edema disorganized arrangement,apoptosis bu RIR,but alleviated by the drug intervention.Bcl-2 and Bax were expressed in the retina of normal rats,after RIR,the expression of Bcl-2 and Bax would be increased;Bcl-2 would increase,but Bax would decrease after durg intervention.Discussion:It appear protective effect on the rats of RIR after administrated by sdiuom p-aescin.