The Research On The Menstruation Situation, The Syndrome Distribution Of TCM And The Related Factors Of 292 Patients With Diminished Ovarian Reserve

?Objective?292 patients with Diminished Ovarian Reserve are surveyed in this paper.The related data are sorted,collected and statistically analyzed.Accordingly,the TCM syndrome distribution,clinical common symptoms and its related influencing factors of Diminished Ovarian Reserve are preliminary discussed in this paper,which provides evidence support for syndrome differentiation and treatment,and offers epidemiology data for scientific research.?Method?After the early diagnostic research by epidemiological methods,the " TCM syndrome and related factors of patients with Diminished Ovarian Reserve " has been to study out.Expert discussion was carried out in order to further optimize the questionnaire.The epidemiological studies of Diminished Ovarian Reserve have been performed.292 patients with Diminished Ovarian Reserve in Chengdu University of Traditional Chinese Medicine Hospital outpatient service of department of gynaecology were collected from February 2015 to February 2017.Relevant data was collected and dedicated database was established.With frequency analysis and cluster analysis to study the the common symptoms of TCM syndrome types and the law of distribution of symptoms of patients with Diminished Ovarian Reserve,using IBM.SPSS21.0 statistical software.Patients with Diminished Ovarian Reserve can be divided into normal menstruation group and menstrual abnormalities group according to the patient's menstrual condition.Take the nonparametric test(the Mann-Whitney test)comparison between the two groups of patients with sex hormone levels.Age,weight,age of menarche,mother menopause age,pregnant times,uterine cavity operation rate,and self-evaluation of depression and anxiety self-assessment menstrual conditions were observed for The effect of menstruation of the patients with Diminished Ovarian Reserve using nonparametric test(the Mann-Whitney test).ovarian surgery history,sleep,mumps history and history of adverse pregnancy menstrual conditions were compared for The effect of menstruation of the patients with Diminished Ovarian Reserve using chi-square test.?Result?1.The average age of 292 patients with Diminished Ovarian Reserve is 32.31±5.04 years old.The average BMI is 21.93±2.40 years old.2.The average first menstruation age of the 292 patients with Diminished Ovarian Reserve is 13±1.351 years old.Menstruation is normal in 158 patients,abnormal menstruation in 134 patients.The average mother menopause age of 292 patients with Diminished Ovarian Reserve is 49.23±49.23 years old.3.The average number of pregnancy of 292 patients with Diminished Ovarian Reserve is 1.73±1.628 times.There are 205 cases of patients with a history of pregnancy,among them,160 cases of patients with a history of abortion.4.In 292 patients with Diminished Ovarian Reserve,there are 196 patients with a history of gynecologic surgery,29 cases of patients with ovarian surgery history,182 patients with a history of uterine surgery.There are 105 patients who have had a uterine operation.5.In 292 patients with Diminished Ovarian Reserve,there are 119 cases of depression,81 cases of anxiety,156 cases of falling asleep at 22:00-23:00,244 cases of occasional exercise.6.In 292 patients with Diminished Ovarian Reserve,there are 13 cases with a history of mumps,96 cases with a history of adverse pregnancy.7.292 patients with Diminished Ovarian Reserve of FSH level is 9.73±5.01 m IU/ml;LH level is 4.27±3.51 m IU/ml;FSH/LH level is 2.85±1.35;E2 level is 57.22 ±67.91pg/ml;AMH level is 1.22±1.13ng/ml.8.According to the preliminary,FSH levels(FSH?10m IU/ml),FSH/LH(FSH<10miu/ml,2?FSH/LH < 3 and FSH/LH?3)and AMH compared between normal menstrual group and abnormal menstruation,the difference is statistically significant(P<0.05);FSH levels(FSH<10m IU/ml),LH and E2,there are no statistically significant difference(P>0.05).9.292 patients with Diminished Ovarian Reserve of the main TCM syndrome types have kidney liver depression syndrome in 78 cases,kidney liver depression and blood stasis syndrome in 74 cases;composite card type in 264 cases;syndrome of intermingled deficiency and excess in 254 cases.10.292 patients with Diminished Ovarian Reserve of common symptom have lumbar debility in 218 cases,irritability in 209 cases,insomnia and dreaminess in 204 cases,sensation of chill in 199 cases,cold limbs in 197 cases,forgetfulness in 194 cases,hyposexuality in 179 cases.11.According to the preliminary,age,body mass index,age of menarche,Mother menopause age,pregnant times,self-reported depression,anxiety self-assessment,ovarian surgery history,history of adverse pregnancy and mumps history related to menstruation is not(P>0.05),uterine cavity operation times and sleep time associated with menstrual conditions(P<0.05).?Conclusion?This study preliminarily shows that:1.The age of 292 patients with Diminished Ovarian Reserve is mainly between 28 and34 years old;BMI is concentrated in the normal weight range.2.Most menarche age in 292 patients with Diminished Ovarian Reserve is normal.Menstrual abnormalities less than Menstruation normal,which mainly is hypomenorrhea.Most mother menopause age is normal.3.The percentage of 292 patients with Diminished Ovarian Reserve who had never been pregnant was the largest.Patients with a history of pregnancy have a history of abortion.4.The most common procedure for gynecologic surgery in 292 patients with Diminished Ovarian Reserve is uterine surgery.5.Depression and anxiety were more common in 292 patients with Diminished Ovarian Reserve.Most patients sleep time is normal.Most of the occasional exercise.6.The FSH levels(FSH?10m IU/ml)and FSH/LH(When FSH<10 10 m IU/ml,2?FSH/LH < 3 or FSH/LH?3)of abnormal menstrual group are higher than the normal menstruation group.The AMH levels of abnormal menstrual group are lower than the normal menstruation group.And the difference is not big between the two groups of patients with Diminished Ovarian Reserve in FSH levels(FSH<10m IU/ml),LH,E2 levels.7.292 patients with Diminished Ovarian Reserve one of the most common TCM syndrome type of kidney liver depression and kidney liver blood stasis.TCM syndrome type is given priority to with composite card type.Disease of sex of factors is the most.8.292 patients with Diminished Ovarian Reserve of traditional Chinese medicine(TCM)is the most common symptoms of lumbar debility,irritability,insomnia,much dream,chills,afraid of the cold,cold limbs,forgetfulness,loss of libido.9.Uterine cavity operation times,sleep time in patients with Diminished Ovarian Reserve in the menstruation situation has an effect,and age,BMI,age of menarche,mother menopause age,pregnant times,self-reported depression,anxiety self-assessment,ovarian surgery history,history of adverse pregnancy and history of mumps in patients with Diminished Ovarian Reserve does not affect menstruation situation.