| Objective:The clinical effects of oral waist and leg pain granules and anti-inflammatory analgesics on postoperative residual disease of lumbar disc herniation were compared between 5-7 days before operation and 7-12 days after operation,and discuss the mechanism of its action,it also provides some reference data for the treatment of lumbar disc herniation by Chinese and Western medicine.Methods:Using a retrospective analysis method,50 cases of 2014.03-2015.03(the "lumbago and leg pain Granule" in Wendeng,Shandong Province,which have not been used in clinical),were taken as the control group for the treatment of the lumbar intervertebral disc herniation,2015.04-2016.03(at that time,"waist and leg pain Granule" has been applied to clinical)50 cases of lumbar disc herniation treated in our department are the experimental group;Extirpation of nucleus pulposus in all two groups,the preoperative and postoperative routine treatment regimen were consistent;The patients in the experimental group had two times a day,one day,one box and the Nimesulide Dispersible Tablets(Hainan Kang Zhi Pharmaceutical Co.,Ltd.),three times a day,one tablet at a time,and one day by oral lumbago and leg pain granules in the perioperative period(self-made free fried granules in Wendeng bone Hospital of Shandong province);Patients in the control group were given oral Nimesulide Dispersible Tablets(Hainan Kang Zhi Pharmaceutical Co.,Ltd.)three times a day,one tablet at a time;the general data of two groups of patients and the first day visual analogue score(VAS)and the Japanese Orthopaedic Association Scores(JOA)were compared with the Department of orthopedics Association of Japan;the improvement rates of VAS and JOA were compared between the two groups on seventh days,14 days,30 days and 90 days after operation,the ODI(Oswestry disability index)score was used to assess the functional status of the patients;All data were analyzed by SPSS 20 software,with mean + standard deviation(mean deviation),Measurement data using t test,Comparison of chi square test for counting data,t is considered that P<0.05 has statistical significance,and P > 0.05 does not have statistical significance.Result:The 100 patients completed the test very well and completed the 90 day follow-up,two groups of subjects' height,age,weight,lesion location,Visualanalogue,VAS,and the assessment of Japanese Orthopaedic Association Scores(JOA)in the Department of orthopedics of Japan(JOA)were analyzed statistically,there was no statistical significance in the difference P > 0.05,so the two groups of patients have comparability,the improvement rate of residual leg pain in the experimental group was 100%,which was significantly better than 84% in the control group,and P<0.05 was statistically significant,the effective ra te of numbness in the lower extremities was 30%,which was better than 26.6% in the control group,7 days,14 days,30 days and 90 days after operation,two groups of patients received VAS pain score,the VAS of the patients in the experimental group was 6.1 0±1.33,4.30±1.88,2.80±1.11,1.50±0.63,the control group was6.8±1.43,2.6±0.73,2.1±0.63,1.10±0.33,the pain level of the experimental group was significantly lower than that of the control group,and P<0.05 was statistically significant,the improvement rates of VAS and JOA in the experimental group were higher than those in the control group 7 days,14 days,30 days and 90 days after operation,there was a significant difference in the improvement rate of VAS score between third days and 14 days after operation(P<0.05),and there was no significant difference in the improvement rate of JOA score(P>0.05),the ODI scores of the 7,14,30,and 90 days after the operation were42.50±9.33,32.50±5.19,19.52±3.35,8.50±1.60,respectively,and the control group was 40.50±7.33,23.50±3.63,13.50±2.33,7.50±1.53,respectively.The ODI score of the test group was obviously superior to the control group,and the P<0.01 had statistical meaning.Conclusion:(1)During the perioperative period,the waist and leg pain granules in our hospital obviously alleviated postoperative residual lumbago and leg pain and lower limb sensation.It has improved the quality of life of patients,safe and effective,and is worthy of clinical promotion.(2)The residual symptoms of postoperative lumbar disc herniation treated by Integrated Chinese and Western medicine are obviously better than those of Western medicine alone.On the basis of oral administration of Nimesulide Dispersible Tablets,the effect of waist and leg pain granule was obviously better than that of single medication. |
PDF Full Text Request