Clinical Analysis Of 155 Cases Of Primary Small Intestinal Diseases Confirmed By Pathology

ObjectiveTo investigate the clinical features and the diagnostic methods of primary small intestinal disease.MethodsThe clinical data of 155 patients with primary small intestinal diseases diagnosed by pathological examination were collected for this retrospective study.All patients were admitted to the First Affiliated Hospital of Chongqing Medical University from January 2011 to December 2015.We analyzed each patient's complete clinical data contained etiology,pathological diagnosis,predilection site,main clinical symptoms,supplementary examination and final diagnosis in the study.ResultsThe common cause of primary small intestinal disease was the tumor,accounted for 68.39%of all cases,and most of them were malignant tumor.Small intestinal diverticulum,Crohn's disease,intestinal tuberculosis,accounted for 18.29%,5.14%,3.87%,respectively.Other rare causes were acute hemorrhagic necrotizing enteritis,intestinal polyps and erosive enteritis.The proportion of primary small intestinal disease in male and female was 52.90%,47.02%,respectively.The average age was 59.46+16.48 years.There was no significant difference in gender,age and etiology,P<0.05,the chi square values were 0.027,4.230 respectively.Abdominal pain was the most common symptom accompanied by gastrointestinal bleeding,weight loss,nausea,vomiting,abdominal mass and fever,accounted for 61.94%,38.06%,26.45%,21.94%,17.42%,12.90%,respectively.There was no significant difference in age and symptom,P<0.05,the chi square values was 8.020.The positive diagnostic rate of capsule endoscopy,abdominal CT and small intestinal enteroscopy were 72.73%,66.91%and 62.50%respectively.The positive diagnostic rate of abdominal CT combined with capsule endoscopy or small intestinal enteroscopy were 90%and 83.33%respectively.ConclusionThe clinical manifestations of primary small bowel diseases were lack of specificity,and small bowel tumor was the main cause of primary small intestinal diseases.Small intestinal disease should be highly suspected in patients with abdominal pain and gastrointestinal hemorrhage.Combined abdominal CT and endoscopic examination may improve the diagnosis rate of primary small intestinal diseases.