Clinical Features And Diagnosis Of Adenocarcinoma Of Small Intestine In 82 Cases

Objective To explore the clinical features and diagnosis of aden -ocarcinoma of small intestine.Methods Retrospective analysis of the clinicopathological data for 82 cases with adenocarcinoma of the small intestine was conducted.The relations of age,gender,diameter and malignant degree,infiltrated extent and metastasis of adenocarcinoma were analysed by SPSS13.0 package.Results Among the 82 cases,there were 75 cases occurred at duodenum,5 cases at the jejunum,2 cases at ileum.Clinical presentation included abdominal distention,abdominal pain,anaemia and athrepsy.Distant or lymph node metastasis was occured in 33 cases.Well differentiated adenocarcinoma was 18 cases.Moderately differentiated was 33 cases.Poorly differentiated and undifferentiated were 31 cases.There was no difference in age and gender among cases.The diameter of poorly differentiated and undifferentiated adenocarcinoma were more than the well differentiated(P＜0.01)and moderately differentiated(P＜0.01).There was no difference in diameter between moderately differentiated and well differentiated adenocarcinoma(P＞0.05).The diameter of infiltrated full-thickness of adenocarcinoma was more than infiltrated muscular tunic(P＜0.05)and mucous tunic and submucous layer(P＜0.01).There was no difference in diameter between adenocarcinoma of infiltrated muscular tunic and mucous tunic and submucous layer(P＞0.05).There was no difference in diameter between the two cases of none and lymph node and distant metastasis(P＞0.05). Preoperative diagnosis was 57 cases by endoscope.25 by operations research.Conclusions Duodenal adenocarcinoma was the most common adenocarcinoma of the small intestine.There were no features of clinical sign in the early stage.There was no relation between malignant degree,infiltrated extent of adenocarcinoma and age and gender of patient,but was to diameter of adenocarcinoma.There was no relation between metastasis and age,gender and diameter of adenocarcinoma.Endoscope and operations research are the main means of diagnosis.To enhance the diagnostic rate of primary small intestinal tumor,gastroduodenoscopy,small intestinal barium meal examination,CT and MRI should be used together.