Effect Of Intraoperative Warming Infusion On Postoperative Recovery Quality,Blood Glucose And Blood Lactate In Middleaged And Elderly Patients Undergoing Colorectal Tumour Surgery

Objective:To observe the effect of different temperature of fluids on the quality of postoperative recovery,blood glucose and blood lactate in middleaged and elderly patients undergoing colorectal tumour surgery.Methods:60 patients with elective open colorectal surgery under general anesthesia,ASA II-III,were recruited and randomly divided into warming infusion group(n=30),which were infused with fluids of 41?by heating apparatus,and control group(n=30),with fluid at room temperature(22-25?),without special intervention.We observed the perioperative temperature,blood glucose and blood lactate changes and used post-operative quality recovery scale(PQRS)to evaluate the recover of physiology,cognitive function,activities of daily living,and the occurrence of anxiety,depression,pain,nausea and vomiting between two groups at 15 min and 40 min after extubation and the 1,3,7 day after surgery.Time of spontaneous breathing,time of eye opening on call,time of fully conscious,extubation time and steward score and the post-anesthesia care unit residence time were recorded too.Results:Compared with control group,warming infusion group had higher temperature at 90 min after began of surgery,extubation time,15 min,40min after extubation(p<0.05).Hypothermia incidence was significantly lower at extubation time,15 min after extubation in warming infusion group(p<0.05).The blood glucose of the warming infusion group was significantly lower than that of the control group at extubation time,15 min after the extraction(p<0.05),and the blood lactate in the warming infusion group was significantly lower than that in the control group at extubation time(p<0.05).Compared with control group,time of spontaneous breathing,time of eye opening on call,time of fully conscious,extubation time and post-anesthesia care unit residence time in warming infusion group were significantly shorter,the steward score were higher(p<0.05).The occur of pain at 15 min,40min after operation was lower in warming infusion group(p<0.05).There was no significant different of physiological function,nausea and vomiting,anxiety,depression and activities of daily living and cognitive function recovery between two groups at any times(p>0.05).Conclusion:In middleaged and elderly patients undergoing colorectal tumour surgery,intraoperative warming infusion can prevent the occurrence of hypothermia,reduce the increase of blood glucose and lactate,and improve the postoperative recover quality and reduce the occurrence of pain in the recovery period.But it has no influence in the physiological function,nausea and vomiting,anxiety and depression,activities of daily living and cognitive function.