| Objective: To translate the English version of Sarcopenia screen questionnaire(SARC-F)into Chinese,and to test the reliability and validity of the questionnaire.Based on the analysis of the influencing factors of the disease,to evaluate the effectiveness of factors on symptoms in elderly with sarcopenia.Using meta-analysis to explore effect of exercise therapy on symptoms of old adults with sarcopenia,to provide reliable evidence-based basis for the old adults with sarcopenia to make specific and reasonable exercise program.Methods:1 The SARC-F was authorized by original author,then according to the strict process,SARC-F was translated into Chinese and cross-cultural adapted.A total of 300 old adults in community,which aged 65 years old and above were recruited using convenience sampling method,to test the reliability and validity of the SARC-F questionnaire.2 Using the sex,age,BMI,nature of work before retirement,living conditions,daily exercise,protein and vitamin D intake,numbers of chronic disease as independent variables,a logistic regression was performed to analyse data and explore the main influence factors in elderly of sarcopenia.3 Using meta-analysis to inquire into the effectiveness of exercise therapy on symptoms of aged patients with sarcopenia.Results:1.After cross-cultural adaptation,the differences between Chinese and English are coordinated.According to the suggestions of experts and participants,the relevant contents of item 1 and 2 in the questionnaire aremodified.Pre-testing showed promising results concerning the psychometric properties of the SARC-F.Cronbach's a for the questionnaire was 0.849.According to factor analyses confirmed two-dimensionality of the questionnaire,and the cumulative variance contribution rate was 65.263%.As for the association between the SARC-F and FRAIL questionnaire,Spearman's correlation coefficient was 0.878.The content validity index was0.9.The Cronbach's a coefficient of 0.829,and the Cronbach's a coefficient of two factors was 0.901,0.824,respectively;and test-retest reliability 0.853.2.The Chinese version of SARC-F questionnaire was used to investigate the prevalence of sarcopenia among the elderly in the community,and mean value of the SARC-F score was 1.36±0.88.In sarcopenia group has 72 elderly,the morbidity is 24%.Univariate analysis showed that there was a significant difference with sex,age,BMI,daily exercise,vitamin D intake,making sunlight,numbers of chronic disease between sarcopenia group and non-sarcopenia group.Using logistic regression analysis,odds ratios of these significant varibles were estimated.Age,BMI,numbers of chronic disease were the risk factors for sarcopenia.Regular outdoor exercise,adequate protein intake,adequate vitamin D supplementation were the protect factors for sarcopenia.3.We identified 10 studies.the results showed that 10 studies were qualified.A total of 532 sarcopenic people were included(male:305,female:227).The meta-analysis results suggested that:(1)Combining exercise with multiple exercise patterns may improve skeletal muscle mass[WMD=0.80,95%CI(0.29,1.31),P=0.002] and upper limb muscle strength[WMD=6.14,95%CI(2.40,9.87),P=0.001] in elderly patients with sarcopenia;(2)Exercise therapy can significantly improve the lower limb muscle strength in elderly patients with sarcopenia [WMD=2.65,95%CI(1.46,3.84),P <0.0001];(3)Exercise therapy did not improve the balance ability of the elderly patients with sarcopenia [SMD=0.76,95% CI(-0.26,1.78),P=0.15].Conclusions:1.The Chinese version of SARC-F questionnaire showed good reliabili-ty and validity.providing a reliable tool for rapid screening of the elderly with sarcopenia in community,which can help the medical personnel and family members to identify the early stage of sarcopenia and provide a basis for the prevention and treatment of sarcopenia in elderly.2.Exercise therapy has effect on improving the symptoms of elderly with sarcopenia.Suggestions according to different training objectives,an exercise plan for elderly with sarcopenia.Improve the symptoms of sarcopenia and the quality of life of the elderly. |
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