Analysis Of The Sonographic And Clinicopathologic Features Of Papillary Thyroid Microcarcinoma Based On Tumor Size

Objective:To retrospectively compare the sonographic and clinicopathologic features of papillary thyroid microcarcinoma ?5mm and >5mm to understand the biological behavior of them and improve the diagnostic value of ultrasonography.Methods: A total of 1055 cases of PTMC between June 2015 and February 2017 was included in the study.Based on their sonographic and clinicopathologic features,univariate and multivariate analysis were used to find the relationship between them.Results: Cervical lymph node metastasis(21.4vs43.5%),bilaterality(12.4vs24.4%),extrathyroidal extension(1.1vs8.5%),capsular invasion(4.4vs16.7%),were more frequent in PTMC>5mm.For the sonographic features,ratio of length/width(66.4vs56.3%),no halo ring(97.1vs94.3%),no hypervascularity(52.1vs42.1%)were more frequent in PTMC?5mm,calcification(51.4vs67.9%),hypervascularity(17.2vs23.6%)were more frequent in PTMC>5mm.Multivariate analysis showed that for PTMC?5mm,male gender(P<0.001)and bilaterality(P=0.003)were related to Cervical lymph node metastasis,for PTMC>5mm,multifocality(P=0.015),calcification(P<0.001)were related to Cervical lymph node metastasis.Conclusion:The sonographic features of PTMC were similar,the clinicopathologic features of PTMC?5mm were less aggressive than those of PTMC>5mm,we should pay more attention to the patients who is male and has calcification.We should not be overlooked when the PTMC >5mm are hypervascularity and multifocality and PTMC ?5mm are bilaterality and capsular invasion.