Relativity Between Cognitive Impairment And Non-disabling Cerebrovascular Diseases Combined With Cerebral Microbleeds

Objective:To analyze and discuss the relationship between non-disabling cerebrovascular events with cerebral micro-hemorrhage and cognitive function.Methods:A total of 50 non-disabling cerebrovascular events admitted to our hospital from January 2017 to September 2017 were enrolled in this study.20 patients with no cerebrovascular disease and no obvious lesions were selected randomly,all of these 70 patients were selected as study objects.T1WI?T2WI?FLAIR?DWI?SWI scans were performed on all patients in the study,according to the SWI test results,fifty patients were divided into two groups.There are 31 cases of Non-disabling cerebrovascular events with micro-hemorrhage.And 19 cases of non-disabling cerebrovascular events without micro-hemorrhage as the control group.The two groups were measured according to the Montreal Cognitive Assessment(MOCA)and the Mini-mental State Examination(MMSE)to analyze the relationship between cognitive impairment and non-disabling cerebrovascular events with cerebral micro-hemorrhage.Results:1.Among the 50 patients with non-disabling cerebrovascular events,31 patients had micro-hemorrhage with a positive rate of 62%.2.There was no significant difference in MMSE and MOCA scores between the control group and the nomal group(P>0.05),while the MMSE and MOCA scores between the control group and the normal group and the group with microbleeds were significantly different(P<0.05).Comparing the total score of MMSE and MOCA,the group wifth micro-hemorrhage was significantly lower than the group without micro-hemorrhage(P<0.05).3.There were significant differences in MMSE and MOCA scores between middle grade ? microbleeds group and grade ? grade ? microbleeds group in non-disabled ischemic cerebrovascular events group(P<0.05).4.There were significant differences in the five cognitive fields of delayed memory,visual space and executive function,language,abstraction and orientation between the group with microbleeds and the normal group and the group without microbleeds(P<0.05).5.Cognitive decline of non-disabling cerebrovascular disease with microbleeds in the presence of hypertension was 4.136 times greater than that of non-combined bleeding.The decline of cognitive function in the non-disabling cerebrovascular disease with the ?-level cerebral microbleeds was 4.749 times of the non-combined bleeding.Conclusions:1.The incidence of non-disabling cerebrovascular events in patients with cerebral micro-hemorrhage is relatively high.2.Patients with non-disabling cerebrovascular events with micro-hemorrhage have varying degrees of cognitive impairment.The greater the number of positive patients with cerebral micro-hemorrhage,the more obvious the cognitive impairment.3.Cognitive impairment associated with cerebral hemorrhage associated with non-disabling ischemic cerebrovascular events was characterized by delayed memory,visual space and executive function,language,abstraction and orientation.4.The degree of hypertension and microbleeds may be independent risk factors of cognitive dysfunction caused by non-disabled cerebrovascular disease combined with micro-hemorrhage.