Analysis Of Clinical Characteristics And Prediction Indexes Of MS Patients With Phlegm-dampness Syndrome Of Polycystic Ovary Syndrome

Objective:Find out the best predictor of MS in phlegm-dampness syndrome PCOS by comparing the clinical indexes and the predictor indexes of MS patients with phlegm-dampness syndrome PCOS to provide a theoretical basis for the occurrence of MS.Subjects and Methods:455 patients of phlegm-damp syndrome PCOS in the First Affiliated Hospital of Heilongjiang University of Chinese Medicine from August 2013 to December 2017 were selected.According to the diagnostic criteria of MS,BMI and body mass index matched two groups are divided:phlegm-dampness syndrome PCOS + MS group(213 cases)and phlegm-dampness syndrome PCOS + non-MS group(242 cases).Collect data and use SPSS 22.0 for statistical analysis.Results:(1)The prevalence of MS in phlegm-dampness syndrome PCOS was 46.81%.The highest incidence of MS components in phlegm-dampness syndrome PCOS was abdominal obesity,followed by dyslipidemia,elevated blood pressure and fasting blood glucose.(2)The levels of SDP,DBP,WC,HC,WHR,FBG,2h PBG,IR,FINS,2h INS,TG,TC,LDL,ApoB,LDL/HDL,ApoB/ApoA,TG/HDL,TC/HDL,LAP and The incidence of black acorn bark in MS group were higher than those in non-combined MS group(P<0.05).SHBG,HDL,ApoA,LP(a)levels decreased,the difference was statistically significant(P<0.05).(3)ApoB/ApoA,LDL/HDL,LAP,TG/HDL,TC/HDL were positively correlated with DBP,WC,BMI,FBG,2h PBG,IR,FINS,2h INS,TG,TC,LDL and ApoB,with a negative correlation with ApoA and HDL,and the difference was statistically significant(P<0.05).(4)Through to the WC,SDP,DBP,GS,TG,HDL and LDL/HDL ApoA/ApoB,LAP and TG/HDL,TC/HDL ROC curve analysis,shows AUC and Youden index of TG/HDL were the largest.(5)Compared with the AUC of TG/HDL,TG,TC/HDL,HDL,LDL/HDL and LAP,TG/HDL and other five indicators were statistically different(P<0.05).Conclusions:(1)The incidence of abdominal obesity and lipid metabolism was higher in patients with phlegm-dampness syndrome PCOS combined with MS.(2)The patients with phlegm-dampness syndrome PCOS combined with MS were significantly impaired in glucose metabolism,and insulin resistance was severe.(3)Compared with WC,SBP,DBP,TG,HDL,GS,LDL/HDL,TC/HDL,ApoB/ApoA and LAP,TG/HDL≥1.53 which had the highest predictive value for the occurrence of MS in patients with phlegm-dampness syndrome PCOS.