The Historical Evolution Of Etiology And Pathogenesis Of Malignant Tumors In Traditional Chinese Medicine

Malignant tumor has become the most dangerous disease to people life and health,etiology and pathogenesis reflects the acknowledgement of disease essence in Traditional Chinese Medicine(TCM),the curative effect on malignant tumor depends on the accurate grasp of the malignant tumor etiology and pathogenesis.This study,based on ancient and modern medical literature,focus on the etiology and pathogenesis,the research in different periods of the acknowledgement of the etiology and pathogenesis of malignancy in TCM,shafted by time,combing the historical development of ancient acknowledgement of cancer pathogenesis.And use the frequency statistics and correlation analysis method,based on the periodical literature,high incidence of lung cancer,gastric cancer,liver cancer,colon cancer,breast cancer deepening the cognition on etiology and pathogenesis of malignant tumors.The literature collation of ancient classics shows that the ancestors'acknowledgement of tumor experienced the process from the gods to the gradual medical exploration.Qin and han dynasties,the acknowledgement of cancer pathogenesis is related to exogenous,internal injuries,modern,eating,living,etc,among them with cold evil and blood stasis is more,and with the five elements theory to interpret pathological mechanism.From Three kingdom to Tang dynasty,expand the acknowledgement of cancer pathogenesis,produced such as "mistook medical" "heat and blood stasis" poison "storage" of new ideas,and to recognize the characteristics of tumor diseases,treatment records increased during this period,using the formulas more mature.From Song to Yuan dynasty,the acknowledgement has unique insights,more related to modern,spleen and stomach,specimen between good and evil,phlegm and blood stasis and toxin factor,etc.,the word "cancer" in this period and was the meaning of tumor,but has not been widely used.During the Ming and qing dynasties,there was a deep acknowledgement of the development of tumor's long course of disease,and it was believed that different etiology and pathogenesis existed in different stages,and different treatment methods should be adopted.In the period of the republic of China,there was no great progress in the acknowledgement of tumor in TCM,but under the impact of western medicine,it was clearly recognized that tumor was different from the general mixed diseases of internal injuries and surgical ulcers,and had its particularity.Modern research based on the statistical results show that:(1)Lung cancer:The acknowledgement of etiology and pathogenesis of lung cancer in recent 40 years is "the deficiency of lung " for the majority opinion.Opinion "Yin deficiency of lung" most evolved into "Qi deficiency of lung" point of view in the majority,sometimes accompanied by "deficiency of Pi" at the same time.Pay more attention to phlegm evil,and gradually with the blood stasis and toxin factor.(2)Gastric cancer:Almost 30 years,the acknowledgement of the etiology and pathogenesis of gastric cancer was"deficiency of stomach" for the majority of views,gas hemopenia for more,gradually"Qi deficiency "was more,always had opinion of "Yin deficiency",the " poison "can't be ignored,"blood stasis""hot",and all fit for disease,closely related to the liver and spleen,treatment of how to juggle.(3)Liver cancer:Pathogenesis of liver cancer is complicated,the acknowledgement of the nearly 40 years by the general Qi pay equal attention to,give priority to both the evolution,the imaginary is "Yin deficiency of liver(and kidney)" more,more than the reality gradually clear "hot" and "blood stasis poison" for a disease.(4)Colorectal cancer:Among 30 years,the acknowledgement of the etiology and pathogenesis of bowel cancer,this followed by clear for the temper,and for the development of "spleen-deficiency kidney Yin deficiency" and gradually in the majority of its "stasis poison",and again in order to "hot" point of view in the majority.(5)Breast cancer:Among 30 years,the acknowledgement of the etiology and pathogenesis of breast cancer gradually is given priority to with standard to the virtual to real,gradually come to "Yin" and "blood stasis" point of view,and also for the development of "liver and kidney Yin deficiency" and "virtual" temper,standard but by"hot poison" expand for the "toxic heat phlegm and blood stasis",and deepen the"phlegm and blood stasis and knot" and "empty poison invasion" point of view.Therefore,the etiology and pathogenesis of malignant tumor is virtual combined real.This focus in different periods have different acknowledgement,statistical analysis,according to the results of the trend of history is mainly by the real change for this deficiency.Spleen and stomach function at the same time in the pathogenesis and treatment of malignant tumor has a significant impact,and "qi and blood stasis" is the important point of the development history of malignant tumor etiology and pathogenesis.The theory of "cancer toxicity" is a relatively systematic epistemology of etiology and pathogenesis in recent years.