Effects Of Extracts Of Lonicerae Flos And Scutellariae Radix On Growth In Broilers

The extract of lonicerae flos and scutellariae radix is an extract of traditional Chinese medicinal materials,chlorogenic acid and baicalin are the main components.It is a clearing and detoxifying drug commonly used by Chinese veterinarians.Research and application at home and abroad had confirmed their various effects such as anti-inflammatory,antibacterial,antibacterial,antiviral,anti-metamorphic,anti-oxidation,antipyretic and analgesic,improving microcirculation and promote metabolism.In the production,the extract of lonicerae flos and scutellariae radix,which inhibits the inflammatory reaction induced by xylene,inhibits the growth of Escherichia coli and Staphylococcus aureus in vitro and in vivo.To test its application in production,we did the following research:In order to determine the clinical recommended dose of extracts of lonicerae flos and scutellariae radix,five groups of AA+ broilers were fed with different doses of extracts of lonicerae flos and scutellariae radix from low to high,one group of blank control group was fed with normal diet.The results showed that the average weight gain of the 0.50g/kg feed group was the highest and the material to weight ratio was the lowest,too.Based on the results,the clinical recommended dose of the extracts of lonicerae flos and scutellariae radix was 0.50g/kg,and the safety experiment was carried out with 5,3 and 1 times of the recommended doses.The results showed that it did not cause morbidity and death of broilers,and had no adverse effects on the general signs,performance and major organs of broilers,indicating that the clinical using of the extracts of lonicerae flos and scutellariae radix was safety.In order to further test the effects of the extracts of lonicerae flos and scutellariae radix on the growth performance and immune function of broilers,180 one-day-old AA+ broiler chicks were randomly assigned to three groups,which were blank control group(no additive group),positive control group(Beau Lai Hui San)and lonicerae flos and scutellariae radix extract group,each treatment set 6 replicates.The growth performance,blood physical and chemical indicators,immune indexes and intestinal morphology of AA+ broilers were studied at 21 th and 42 th day.The results showed that:1.The effect of the extract of lonicerae flos and scutellariae radix on the growth in broilers.Comprehensive comparison,the whole process of the extract of lonicerae flos and scutellariae radix.can achieve the same performance as the positive control group,and also can reduce the death rate of broilers.2.The effect of extract of lonicerae flos and scutellariae radix on blood physical and chemical indicators of broilers.At 21 days old,the serum triglyceride content and serum total cholesterol content of broiler chickens of lonicerae flos and scutellariae radix group were significantly lower than the positive control group and the blank control group(P<0.05).At 42 days of age,the total cholesterol content in the extract of lonicerae flos and scutellariae radix was lower than in the blank control group,but the difference was not significant(P>0.05).In the case of high-density lipoprotein,the difference between the groups was not significant(P>0.05),but the extract of lonicerae flos and scutellariae radix was higher than the blank control group;The low-density lipoprotein cholesterol of the extract of lonicerae flos and scutellariae radix was significantly lower than the positive control group and blank group(P<0.05).At 21 days,the content of T-AOC was significantly higher than the control group(P<0.05).At 42 days,the serum level of T-AOC in the extract of lonicerae flos and scutellariae radix was the highest.Compared with the blank group and the positive control group,the extract of lonicerae flos and scutellariae radix can significantly increase the content of GSH-Px and SOD in the serum of broiler chickens.3.The effect of extract of lonicerae flos and scutellariae radix on immune index and intestinal morphology of broilers.At 21 days of age,the serum IgA,IgG and IgM of the extract of lonicerae flos and scutellariae radix were higher than the blank control group and the positive control group.At 42 days of age,the IgG content of the extract of lonicerae flos and scutellariae radix was significantly higher than the positive control group and the blank control group(P<0.05);the lysozyme content of the extract of lonicerae flos and scutellariae radix was higher than the positive control group and the blank group.At 42 days of age,the height of duodenum and jejunum villi and the ratio of villus/crypt in the extracts of lonicerae flos and scutellariae radix and the positive control group were significantly higher than those in the blank control group(P<0.05).The above results indicated that the addition of the extract of lonicerae flos and scutellariae radix to the broiler can decrease the material to weight ratio,reduce the rate of death,reduce blood cholesterol,increase the content of GSH-Px and SOD in serum,and increase the height of the fluff.Therefore,the mixed feed of lonicerae flos and scutellariae radix in the diet can promote the growth of broilers,regulate fat metabolism,enhance the body's antioxidant capacity and immune function,and improve the structure of intestinal flora.