| Purpose : Collecting cases Affiliated Hospital of Liaoning University of Traditional Chinese Medicine Endocrinology hospitalized peripheral neuropathy in type 2 diabetes patients, their retrospective analysis, study the relationship between TCM syndrome and related sub-indices. For the future to be more accurate, comprehensive understanding of the relationship of diabetic peripheral neuropathy TCM clinical status and clinically relevant indicators for the future to better guide prevention and treatment of diabetic peripheral neuropathy in Chinese medicine to provide ideas.Material and method:Collected from March 2014 to December 2014 in the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine Endocrinology hospital and has been diagnosed as cases of 152 patients with type 2 diabetic peripheral neuropathy. Referring to the 2007 version of the Chinese Medical Association, issued by the China Medical Publishing House "TCM Diabetes Prevention Guide" and Ji-Shaoliang edited by People’s Health Publishing House version of the 2002 "Chinese Diagnostics" in traditional Chinese medicine for diabetic peripheral neuropathy dialectical and reference treatment experience and the specific circumstances of the hospital’s patients, diabetic peripheral neuropathy group into deficiency of qi and yin, deficiency of yin and yang, liver and kidney deficiency, damp spleen four groups were recorded for all patients enrolled sex, age, duration, BMI, fasting blood glucose, glycated hemoglobin, triglycerides, cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, blood pressure(systolic blood pressure, diastolic blood pressure, pulse pressure). A retrospective survey methods in hospital medical records, computer data entry is first of all relevant indicators and statistics to establish a database in support of SPSS17.0 statistical softwareunder. Each set of experimental data were presented as mean X S standard deviation(X S) that the groups were compared using ANOVA, homogeneity of variance with LSD test, missing variance t test.Results:1. cases of patients with DPN collected in different TCM syndromes by constituent ratio as follows: deficiency of qi and yin, damp spleen, liver and kidney deficiency, Qi and yin Deficiency is most common, but compared to other groups There was no ignificant(P >0.05).2. The proportion of male and female patients with DPN is 1: 1.26, was not statistically significant(P > 0.05); in the age group of the youngest damp spleen, and the other three groups were statistically significant(P <0.01, P <0.05); heat duration of spleen was significantly higher than Qi and yin Deficiency(P <0.05); damp spleen of BMI gnificantly higher than the other groups(P <0.01). 3. FPG of damp spleen group compared with the other group than the other groups(P <0.05); and Hb H1 c liver and kidney deficiency group was significantly lower than the yin and yang Deficiency(P <0.05).4. Syndromes between the four groups showed no significant difference in blood pressure(P > 0.05), systolic blood pressure on the liver and kidney deficiency alone group and Qi and yin Deficiency was statistically significant(P <0.05).5. C-peptide at 0min, 180 min when damp spleen Qi combination group was statistically significant(P <0.05), 30 min, 90 min, 120 min group when damp spleen qi and yin Deficiency, yin and yang Deficiency, liver and kidney has significant statistical significance(P <0.01) compared to group deficiency. Has significant statistical significance(P <0.01) at 180 min when yin and yang Deficiency compared with the damp spleen.6. Four different TCM syndromes of total cholesterol and low-density lipoprotein was no significant difference(P>0.05),Triglycerides and high-density lipoprotein yin and yang Deficiency is higher than the heat and damp spleen, with statistical significance(P <0.05).7. Complications of type 2 diabetic peripheral neuropathy in diabetic incidence followed in descending order: lower limb arteriosclerosis> Hypertension> carotid atherosclerosis> diabetic retinopathy> dyslipidemia.onclusion:1. DPN pathogenesis not related to gender. 2. DPN pathogenesis of age- related. The elderly to Deficiency and younger Multi- real. Older patients, mostly liver and kidney deficiency type, the young patients were mostly damp spleen type. 3. Heat spleen group longest duration of diabetes. 4. Obesity is the main heat causes the spleen type DPN. 5. Damp spleen and FPG increased incidence type DPN have some relevance. The yin and yang type DPN difficult to control blood glucose. 6. dyslipidemia is a major cause of DPN 7. DPN there are different degrees of insulin resistance, in which patients with DPN heat spleen type most obvious. 8. lower limb arteriosclerosis, carotid atherosclerosis and hypertension are major complication DPN. |
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