Diabetes Peripheral Neuropathy Related Factors And Tcm Syndrome

ObjectiveThrough the clinical observation to the diabetes of Peripheral Neuropathy (DPN), to analyse the patients with DPN about the related factors, such as general situation, biochemical index, merger disease, and to facilitate the medical intervention to early DPN, slow lesions development; Explore DPN namely BiZheng syndrome type distribution characteristics, so as to facilitate the dialectical legislation and prescription medication.MethodsProspectively studied56DPN patients, according to the nerve electricity physical check, resul t groups for highest sens it ivity of nerve electrophysiology check index H reflection as packet basis. Compared the two groups in general situation, the related biochemical index, mergered disease, etc. Refer to the national standard of the People’s Republic of clinical diagnosis and treatment of traditional Chinese medicine (TCM) terminology syndrome in2002, the health of the Chinese herbal medicine new medicine clinical research guiding principle of TCM syndrome diagnostic standard, according to the clinical symptoms, tongue and pul se condi t ion, comprehensive different iat ion c lass if i cat ion. The SPSS17.0statistical software analysis of the results, count data set percentage between compares the chi-square test, and the related factors with Logistic regression analysis.Results1. The longer the duration, the higher glycated hemoglobin (HbA,c), and the less hollow c-peptide, the reflection of the patients with DPN H abnormal rate is high.2. Urine A/C, high sensitive C-reactive protein (HS-CRP), indirect bilirubin (IBID, and uric acid (UA) can reduce H reflects abnormal rate.3. Fasting plasma glucose (FPG)<6.1mmol/L,and systolic blood pressure (SBP)<130mmHg can increase reflected H abnormal rate.4. DPN TCM syndrome factor appear frequency from high to low in turn:kidney deficiency pattern45cases (80.4%), spleen deficiency pattern32patients (57.1%), blood stasis syndrome pattern30cases (53.6%), damp with hot pattern in30cases (53.6%), liver qi stagnation pattern29patients (51.8%), phlegmy wet pattern12cases (21.4%), internal wind pattern in two (3.6%). 5. Common phase and syndrome types appear frequency from high to low in turn: kidney Yin deficiency-damp and hot pattern in25patients (44.6%), kidney Yin deficiency-blood stasis pattern24patients (42.9%), the spleen deficiency liver qi and blood stasis pattern23cases (41.1%), spleen dificiency-blood stasis pattern16cases (28.6%), Yin and Yang inharmony and Yin deficiency produce inner wind pattern two (3.6%).Conclusion1. People with diabetes, especial ly had longer duration, lower SBP, higher HbA1C, lower FPG, lower fasting C-peptide, higher HS-CRP,abnormal UA, abnormal IBIL, abnormal urine A/C, should be regularly screened, to diagnose early DPN and imply earlier medical intervention.2. The pathogenesis of BiZheng is that the root cause is bowels and viscera are deficienct,and the pathogenic factors are excess, for the spleen deficiency, kidney deficiency, and the damp and hot, blood stasis, phlegmy wet. So in the clinical treatment should not merely for dissipate the blood stasis, clear heat and resolving phlegm, should pay attention to fortify the spleen the kidney, to enhance the curative effect.