Analysis Of The Risk Factors Of Anastomotic Leakage After Laparoscopic Assisted Resection For Rectal Cancer

Objective To analyze the high risk factors of anastomotic leakage after laparoscopic assisted resection for rectal cancer and provide a theoretical basis for reducing anastomotic leakage after laparoscopic resection of rectal cancer.Method To collect and analyze the clinical data of the 94 patients who received laparoscopic assisted resection for rectal cancer in the Affiliated Hospital of Qing Hai University from Jan,2016 to Feb,2018.Data collected included patients' age,gender,body mass index,low level of serum albumin,anemia,diabetes,hypertension,ASA(American Society of Anesthesiologists),TNM(Tumor Node Metastasis)stage,the distance from tumor low margin to the anal edge?defunctioning stoma?transanal drainage tube ?treatment measures.Total clinical data was retrospectively analyzed with chi-square test and Logistic regression test.Results The result was 14 of 94 cases with anastomotic leakage after laparoscopic assisted resection for rectal cancer.The incidence rate of anastomotic leakage was 14.9%.Chi-square test showed that the occurrence of anastomotic leakage after laparoscopic assisted resection for rectal cancer was a correlation between gender,age,the distance from tumor low margin to the anal edge,a low albumin level.Chisquare test showed that the occurrence of anastomotic leakage after laparoscopic assisted resection for rectal cancer was no association with hypertension,CEA,ASA,BMI,diabetes,anemia,neoadjuvant chemotherapy,defunctioning stoma,transanal drainage tube.Logistic regression test showed that the occurrence of anastomotic leakage was strongly correlated to gender,age,the distance from tumor low margin to the anal edge,a low albumin level.Conclusion Patients with male patients with rectal cancer,under age 60,the distance from tumor low margin to the anal edge,a low albumin level.(< 35 g/L)were considered as the independent risk factors for the occurrence of laparoscopic assisted resection for rectal cancer,it should be paid enough attention.In general,most of anastomotic fistula could be cured with conservative treatment,in case of conservative treatment is invalid,colostomy is feasible.