| Objective To investigate the clinical characters of peptic ulcer in Tibet.Clinical date was provided for guiding the clinical diagnosis and treatment of peptic ulcer in Tibet region.Methods We analyzed data of 1325 cases of peptic ulcer who diagnosed by endoscopy in the People's Hospital of Tibet Autonomous Region from January 1 to December 31,2015.397 cases of ulcer patients hospitalized in the Department of Gastroenterology of the same hospital from January 1 to December 31,2016 were analyzed.People's Hospital of Tibet Autonomous Region.Results(1)The gastroscopicy detection rate of peptic ulcer was17.09%(1325/7752)in 2015.(2)The number of males(1041/4243,24.54%)was significantly higher than females(284/3509,8.09%)(P<0.05).(3)Duodenal ulcers were more common in the 20-39-year age group(360/587,61.33%),and gastric ulcers in the 40-59-year-old group(270/581,46.47%).(4)Gastric ulcer was predominant in Tibetans(46.67%,532/1140).Han ethnic group was mainly suffered from duodenal ulcer(61.08%,113/185).The difference was statistically significant(P <0.05).(5)There was no significant seasonal variation in the detection rate of PU(P>0.05).(6)The site of duodenal ulcer was more common in the anterior wall of the bulb(334/587,56.91%).Thesite of gastric ulcers of the Tibetans was more common in the angle of the stomach(226/532,42.48%),while the gastric ulcers of the Han nationality was more found in the gastric antrum(28/49,57.14%)(P<0.05).(7)The positive rate of helicobacter pylori infection was76.83%(620/807),which was higher than the national level(51.0%).It was significantly higher in Tibetan(537/652,82.36%)than in Hans(83/155,53.55%)(P <0.05).We analyzed the data of inpatients of PU,which showed that:(8)The hospitalization rate of peptic ulcer patients was 31.48%(397/1261)from January 1 to December 31,2016.Gastric ulcers were more common in 40-59-year age group(76/150,50.67%),and duodenal ulcers were more common in the 20-39-year-old group(121/200,60.50%)(P<0.05).Duodenal ulcers were more common in the anterior wall of the bulb(116/200,58.00%),and gastric ulcers were in the angle of the stomach(67/150,44.67%).Both are consistent with outpatient results;(9)58.19%(231/397)of peptic ulcers had regular abdominal pain,and 40.05%(159/397)had bleeding.Patients with hypertension accounted for 10.33%(41/397).(10)There was no significant difference in the smoking history,drinking history,blood type,helicobacter pylori infection,and the probability of concurrent gastrointestinal bleeding among peptic ulcer patients(P>0.05).(11)22patients(5.54%)had prior history of NSAIDS medication,and 186(46.85%)did not describe related medication history.(12)The bleedinggroup and non-bleeding group were more common in males(P>0.05).(13)The bleeding group(82/159,51.57%)and the non-bleeding group(118/238,49.58%)were more common in the 20-39 age group(P>0.05).(14)The bleeding group(82/159,51.57%)was more common in the disease course ? 6 months,and the non-bleeding group(151/238,63.45%)was more common in the disease course <6 months(P<0.05).(15)The bleeding group was more common in patients with active peptic ulcer(120/159,75.47%).Non-bleeding group was more common in inactive patients(148/238,62.18%)(P<0.05).(16)The helicobacter pylori infection rate(174/238,73.11%)was higher in the non-bleeding group than in the bleeding group(84/159,52.83%)(P<0.05).Conclusions:(1)The gastroscopy detection rate,hospitalization rate,and the proportion of blood emitted from peptic ulcer were higher in Tibet.Males were significantly more than females.The onset age of gastric ulcer was 20 years elder than duodenal ulcer.Types and predilection of peptic ulcers were different in Tibetans and Hans.The positive rate of helicobacter pylori infection in Tibetans was significantly higher than in Hans.(2)There was no significant difference in the smoking history,drinking history,blood type,helicobacter pylori infection,and the probability of concurrent gastrointestinal bleeding among various types of hospitalized peptic ulcer patients.(3)There were differences in disease duration,ulcer stage,and helicobacter pyloriinfection between the bleeding and non-bleeding groups,and there were no significant differences in gender and age. |
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