Investigation And Analysis Of An Outbreak Of Mycoplasma Pneumoniae Infection In A Military School

Background:The outbreak caused by respiratory pathogenic bacteria infection has caused serious threat to human health,which has attracted widespread attention of the society and the public.The Mycoplasma pneumoniae(MP)is one of the common pathogens causing human respiratory tract infection,It can occur endemically and even epidemically worldwide in persons of all ages.Many outbreaks of M.pneumoniae infections have usually occurred in closed or semiclosed cluster population,especially in military bases and schools.An outbreak of acute respiratory infections caused by M.pneumoniae occurred in a military school in Nanchang from August 29 to September 15,2017.The purpose of this study is to investigate the epidemic situation of M.pneumoniae infection in the military school,and to retrospectively analyze the characteristics of this M.pneumoniae outbreak and evaluate the effect of prevention and control measures,so as to provide a better basis for timely identification and effective prevention and control of M.pneumoniae outbreaks in the future.Objectives:1.Analyze the epidemic situation and epidemiological characteristics of M.pneumoniae infection in this military school;2.Analyze the clinical manifestations,laboratory examination results and radiological characteristics of all disease cases;3.Evaluate preventive measures and effects of the M.pneumoniae outbreak in the military school.Methods:An descriptive epidemiological study was used to investigate the outbreak of M.pneumoniae infection in this military school,Collect the epidemiological field survey data of the epidemic situation and the clinical data of all disease cases.Case study of age?soldier sources?native places?teams?accommodation environment?infection situation?isolation and hospitalization situations?history of epidemiological contact?training and curriculum arrangements of these disease cases.Retrospectively analyze the epidemiological characteristics of the M.pneumoniae outbreak and the clinical features of all disease cases.Results:1.In this outbreak disease,there were 112 cases of the disease,of whom 73 were isolated in the school outpatient department,and 39 were hospitalized.29 hospitalized cases were confirmed with M.pneumoniae infection,and others were clinically suspected cases of M.pneumoniae infection.2.The outbreak situation started on August 29,2017 and lasted 18 days,the total attack rate was 15.93%.From September 9th to 14 th was the peak period of the epidemic,with a total of 68 cases,accounting for 60.71% of the total number of disease cases.3.All 112 disease cases were male,with an average age of 20.34±1.60 years old.A total of 108 cases in the First Cadet team with a attack rate of 26.87%,it was significantly higher than other Cadet teams' attack rate,which was 1.32%.In the First Cadet team,the attack rate of soldiers from college entrance examination students was 23.75%,which was significantly higher than the attack rate of the excellent cadets selected by the army,and the northern region soldiers' attack rate was significantly higher than the southern region.4.In the early stage of onset,the most common clinical manifestations of these disease cases was cough and fever,the incidence was 69.64% and 47.32% respectively.Only 8 cases of lung auscultation could hear rale,accounting for 7.14% of the total number of disease cases.The blood routine and chest X-ray examination were normal in 73 school outpatient isolating cases.The laboratory examination results of 39 hospitalized cases showed the percentage of neutrophils increased,the percentage of lymphocytes decreased,and the c-reactive protein increased.36 cases had pneumonia,the inflammatory parts of the lungs were mostly located in the lower lobe of the lung,and the most common type of radiological features was ground glass opacities.5.Comprehensive targeted prevention and control measures and treatment programmes adopted by the military school and hospital.That effectively controlled and prevented the spread of the epidemic,and no new cases had been reported since September 16 th.Conclusion:The outbreak of the epidemic situation at the military school in Nanchang,from August 29 to September 15,2017,was a point source epidemic of acute respiratory infections caused by M.pneumoniae.All desease cases were young men without basic disease,and most disease cases were in the First Cadet team,among which soldiers from college entrance examination students and the northern region soldiers were more susceptible to the disease.The cases showed mild to moderate respiratory infection symptoms,only a few students had pneumonia and no severe cases.Targeted prevention and control measures could effectively prevent the spread of the M.pneumoniae outbreak.