In Xinjiang People Thyroid Stimulating Hormone Level For The Establishment Of The Reference Range

Objective:Thyroid stimulating hormone(TSH)is secreted by the adenohypophysis hormones,main functions including thyroid cell proliferation,thyroid blood supply and the synthesis and secretion of thyroid hormone,and establishes the reference range of THS level of the uygur population in xinjiang,providing a specific basis for the diagnosis of thyroid related diseases in the uygur population.Methods: In October 2015 randomly selected 2654 people in the Xin Jiang urumqi and turpan regions as the research object,through the questionnaire survey to collect general information,increasing measurement and weight,according to the national institute(NACB)biochemical methods used by the guidelines recommend testing thyroid function,finally according to the exclusion criteria included in 1213 healthy people,build xinjiang region population TSH specific reference range,and with 2011 diagnostic criteria recommended by the American thyroid association to compare its role in the evaluation of thyroid dysfunction.Results:1)661 cases of abnormal thyroid function in residents were sampled,including 67.5% of women,5.13% of hyperthyroidism,and 40.16% of hypothyroidism.The positive rate of thyroid binding globulin antibody(TgAb)was 16.33%,and the positive rate of thyroid peroxidase antibody(TPOAb)was 5.87%.Among them,32.5% were males,2.92% were hyperthyroidism and 14.27% were hypothyroidism.The positive rate of TgAb was 7.87%,and the positive rate of TPOAb was 7.45%.2)both urban male and female TSH levels were higher than those in rural areas(P < 0.001);3)in different age groups,the young group(P < 0.05)and the elderly group(P < 0.001)in women serum TSH levels were significantly higher than the male,the difference is statistically significant,the older women serum TSH level was significantly higher(P < 0.001)in young and middle-aged group,the difference is statistically significant.Conclusion: City crowd serum TSH level higher than the rural population TSH level,the young and the elderly group women high serum TSH levels are same age men,including older women group serum TSH level reference range of 3.77(3.37 4.18)(P < 0.001),different gender and TSH levels in all age groups and chemilumine scence ligue 1 work kit has different definition of serum TSH normal range.