| Objective:1.To find the syndrome factors'distribution of the main disease's lacation and property in patients with T2DM combined with PAS.2.To analyze the relation between the main disease's lacation and property with demography or clinical examination in patients with T2DM combined with PAS.Methods:1.Source of reserach objects:Based on the method of cross section,the clinical data of patient with T2DM combined with PAS meeting the inclusion criteria was collected,who visits in the first affiliated hospital of Xiamen university between January 2017 and December 2017.2.our diagnostic information and related data collecting:Used the self-designed general information form and the"four diagnostic information collection form" provived by the Fujian University of Traditional Chinese Medicine(TCM)syndromes of TCM research base,to collect four diagnostic information,demography and clinical examination of 400 in patients T2DM combined with PAS.the corresponding syndrome elements' integral is obtained by inputing these data in the syndrome diffrentiation system.It can be inferred that the syndrome elements' distribution of the main disease's lacation and property in patients with T2DM combined with PAS,according to the standard for evaluation of TCM sydrome elements(the corresponding syndrome elements' integral over 70).3.Statistical Analysis:statistical methods are used to analyze the relations between the main disease's lacation and property syndrome elements in patient with T2DM&PAS and demography or clinical examination by SPSS20.0,which included descriptive analysis,two independent samples t test,chi-square test,multivariate logoistics regression analysis.P?0.05 was a significant difference.Results:1.The research includes 400 cases of patients with T2DM and PAS.2.Among these cases,by TCM syndrome diffrentiation system,340 cases are over 70 points,accounting for 85%of the samples,and the rest under 70 points,accounting for 15%of the samples.3.Among the 340 patients with T2DM combined with PAS,whose syndrome elements'integralover 70,the morbidity of the disease's lacation from high to low as following:kidneys are accounting for 38.5%(154 cases),livers are accounting for 25.75%(143cases),spleens are accounting for 4.5%(18 cases),exteriors are accounting for 4.5%(18 cases),stomachs are accounting for 4%(16 cases),biles are accounting for 2.75%(11 cases),colorectals are accounting for 2.5%(10 cases),bones accounting for 2.25%(9 cases)and meridians are accounting for 1.5%(6 cases).4.Among the 340 patients with T2DM combined with PAS,whose syndrome elements'integral over 70,the morbidity of the disease's property from high to low as following:yin deficiency are accounting for 63.25%(253 cases),heat are accounting for 41.25%(165 cases),yang deficiency are accounting for 35.5%(142 cases),qi deficiency are accounting for 28.5%(114 cases),dampness are accounting for 21.75%(87 cases),blood deficiency are accounting for 20.5%(82 cases),phlegm are accounting for 20.25%(81 cases),qi stagnation are accounting for 12.5%(50 cases),body fluid deficiency are accounting for 10.5%(42 cases),blood stasis are accounting for 9.75%(39 cases),dryness are accounting for 9.25%(37 cases),yang hyperactivity are accounting for 6.75%(27 cases),blood heat are accounting for 4.25%(17 cases),summer-heat are accounting for 4%(16 cases),cold are accounting for 3%(12 cases),incompetence of qi are accounting for 1.5%(6 cases),exogenous wind are accounting for 0.75%(3 cases),excessive fluid are accounting for 0.5%(2 cases),fluid retention syndrome is accounting for 0.25%(1 cases),yang floating is accounting for 0.25%(1 cases).5.Among the 340 patients with T2DM combined with PAS,the percentage of the combination of syndrome elements from high to low as following:four 17.94%),Three(15.59%),Single(14.7%),five(12.35%),two(11.76%),over ten(9.71%),six(7.6%),eight(4.41%),seven(3.52%),nine(2.65%);6.Among the patients with T2DM combined with PAS,the percentage of the deficiency,excess syndrome from high to low as following:both the deficiency and excess syndrome(88%),pure deficiency syndrome(8%),pure excess syndrome(4%);7.The conclusion of multivariate logoistics regression analysis:Age is the risk factor to kidney syndrome element,Age increased by 1 year,the probability of appearing kidney syndrome element increase of 21.4%;FPG is the risk factor to liver syndrome element,FPG increased by 1 mmol/l,the probability of appearing liver syndrome element increase of 12.8%;Age and FPG are the risk factor to yin deficiency syndrome elemen,Age increased by 3 years,the probability of appearing yin deficiency syndrome element increase of 50.3%;FPG increased by 1 mmol/l,the probability of appearing yin deficiency syndrome element increase of 13.5%;SBP and FPG are the risk factor to heat syndrome element,FPG increased by 1 mmol/l,the probability of appearing heat syndrome element increase of 20.4%;SBP increased by 1 mmHg,the probability of appearing heat syndrome element increase of 23.4%;Age is the risk factor to qi deficiency syndrome element,Age increased by 4 years,the probability of appearing qi deficiency syndrome element increase of 77.6%;There is no evidence that there is a correlation between yang deficiency syndrome element and the corresponding datas in the research.Conclusion:1.kidneys and livers syndrome element are main main disease's lacation,yin deficiency?heat?yang deficiency?qi deficiency syndrome element are main main disease's property;three or four combination of syndrome elements are the most common,and both the excessive and the deficiency syndrome is the main TCM syndrome in patients with T2DM combined with PAS in XiaMen.2.Age is the risk factor to kidneys,yin deficiency,qi deficiency syndrome element;FPG is risk factor toliver,yin deficiency,heat syndrome element;SBP risk factor to heat syndrome element,which can be used as objects of clinical intervention. |
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